Results 61 to 70 of about 4,232,184 (292)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stable RK2-Derived Cloning Vectors for the Analysis of Gene Expression and Gene Function in Gram-Negative Bacteria

Molecular Plant-Microbe Interactions, 2001
The construction of several stable RK2-derived cloning vectors for the analysis of gene expression and function in gram-negative bacteria is reported.
Bruno Dombrecht, Jos Vanderleyden, Jan Michiels   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Letter from Lewis Mumford to Herbert Read, December 22, 1960

, 1960
Part of a collection of correspondence between Herbert Read and Lewis Mumford (American historian, philosopher, and literary critic).
Mumford, Lewis, 1895-1990
core   +1 more source

Diversification of plant specific organellar single-stranded DNA binding genes and their roles in mitochondrial genome rearrangements in Arabidopsis and rice

BMC Plant Biology
Background Organelle genome stability is essential for plant development and adaptation. Recombination of repetitive sequences in plant mitochondrial genomes is a key factor influencing this stability and is tightly regulated by nuclear-encoded proteins,
Yingke Hou, Xiaolin Gu, Liyun Nie, Jie Wang, Zhiqiang Wu, Yi Zou   +5 more
doaj   +1 more source

Satellite Camera CCD Read-out System Design, Based on Noise Optimization with Respect to Satellite Limitations [PDF]

فصلنامه علوم و فناوری فضایی, 2010
Satellite camera Charged Coupled Device (CCD) read out system needs a high Signal to Noise Ratio (SNR). This is because of the special and inevitable space imaging payload noises. These noises include CCD noises, satellite noises such as lack of complete
H. Bazrafshan, Sh. Baradaran Shokouhi, B. Ghorbani Vagheii   +2 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Study on Single Event Upset and Mitigation Technique in JLTFET-Based 6T SRAM Cell

Journal of Electrical and Computer Engineering
The effect of single event transient (SET) on 6T SRAM cell employing a 20 nm silicon-based junctionless tunneling field effect transistor (JLTFET) is explored for the first time. JLTFET-based SRAM circuit is designed using the look up table-based Verilog
Aishwarya K, Lakshmi B
doaj   +1 more source

A Durable Hybrid RAM Disk with a Rapid Resilience for Sustainable IoT Devices

Sensors, 2020
Flash-based storage is considered to be a de facto storage module for sustainable Internet of things (IoT) platforms under a harsh environment due to its relatively fast speed and operational stability compared to disk storage. Although their performance
Sung Hoon Baek, Ki-Woong Park
doaj   +1 more source