Results 31 to 40 of about 304,455 (291)

The Effect of Countermeasure Readability on Security Intentions

open access: yesJournal of Cybersecurity and Privacy, 2021
Human failure is a primary contributor to successful cyber attacks. For any cybersecurity initiative, it is therefore vital to motivate individuals to implement secure behavior.
Tim Smit   +2 more
doaj   +1 more source

Language choice models for microplanning and readability [PDF]

open access: yes, 2003
This paper describes the construction of language choice models for the microplanning of discourse relations in a Natural Language Generation system that attempts to generate appropriate texts for users with varying levels of literacy. The models consist
Williams, Sandra
core   +4 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Positivity of Chern classes of Schubert cells and varieties [PDF]

open access: yes, 2014
We show that the Chern-Schwartz-MacPherson class of a Schubert cell in a Grassmannian is represented by a reduced and irreducible subvariety in each degree.
Huh, June
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

An Analysis of the Readability of Public-Facing Information Relating to Prevention of Infectious Diseases by Vaccination

open access: yesBritish Journal of Biomedical Science
PurposeThe readability of public-facing vaccine-related information is an important aspect of health literacy particularly regarding vaccine uptake.
Beverley C. Millar   +4 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

A systematic review and meta-analysis of English language online patient education materials in breast cancer: Is readability the only story?

open access: yesBreast
Background: Online patient education materials (OPEMs) are an increasingly popular resource for women seeking information about breast cancer. The AMA recommends written patient material to be at or below a 6th grade level to meet the general public's ...
Joey Z. Gu   +7 more
doaj   +1 more source

Annual report readability and corporate agency costs

open access: yesChina Journal of Accounting Research, 2018
Annual reports are the main sources of information for outside investors’ investment decisions and enable shareholders to supervise the management. Difficulties with the readability of these reports may therefore have serious consequences.
Jin-hui Luo, Xue Li, Huayang Chen
doaj   +1 more source

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