Results 41 to 50 of about 96,485 (304)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Readability of web-based sources about induced abortion: a cross-sectional study

BMC Medical Informatics and Decision Making, 2020
Background High-quality information is essential if clients who request an abortion are to reach informed decisions and feel prepared for the procedure, but little is known concerning the readability of web-based sources containing such material. The aim
Susanne Georgsson, Tommy Carlsson
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

A small scale study into the effect that text & background colour has on processing and self-correction rates for childrens’ on-screen reading

, 2010
Pedagogical practices in formal educational settings together with the nature of communication technologies in the media and elsewhere mean that children will encounter on-screen typography and screen-based learning opportunities in both formal school ...
Whitehead, David, Vanderschantz, Nicholas, Carss, Wendy Diane, Timpany, Claire   +3 more
core   +1 more source

The effect of age and font size on reading text on handheld computers [PDF]

, 2005
Though there have been many studies of computer based text reading, only a few have considered the small screens of handheld computers. This paper presents an investigation into the effect of varying font size between 2 and 16 point on reading text on a ...
Goodman, J., Brewster, S.A., Gray, P, Gray, P.D.G., ,, Joy Goodman, Iain Darroch, Phil Gray, Darroch, I., Stephen Brewster, Brewster, S, Darroch, I, Goodman, J   +12 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Readability of Hospital Online Patient Education Materials Across Otolaryngology Specialties

Laryngoscope Investigative Otolaryngology
Introduction This study evaluates the readability of online patient education materials (OPEMs) across otolaryngology subspecialties, hospital characteristics, and national otolaryngology organizations, while assessing AI alternatives.
Akshay Warrier, Rohan P. Singh, Afash Haleem, Andrew Lee, David Mothy, Aakash Patel, Jean Anderson Eloy, Brian Manzi   +7 more
doaj   +1 more source

Readability of the written study information in pediatric research in France. [PDF]

PLoS ONE, 2011
BackgroundThe aim was to evaluate the readability of research information leaflets (RIL) for minors asked to participate in biomedical research studies and to assess the factors influencing this readability.Methods and findingsAll the pediatric protocols
Véronique Ménoni, Noël Lucas, Jean-François Leforestier, François Doz, Gilles Chatellier, Evelyne Jacqz-Aigain, Carole Giraud, Jean-Marc Tréluyer, Hélène Chappuy   +8 more
doaj   +1 more source

Arabic L2 readability assessment: Dimensionality reduction study

Journal of King Saud University: Computer and Information Sciences, 2022
Readability is a measure that associates a written text to a reader’s skill or grade level. Readability assessment is very important in the field of second or foreign language (L2) learning.
Naoual Nassiri, Abdelhak Lakhouaja, Violetta Cavalli-Sforza   +2 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source