Results 81 to 90 of about 534,792 (320)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Theoretical Views Underlying the Selection of Classroom Activities: Paying Attention to the Classroom of English Literature in EFL Context

open access: yesTEFLIN Journal, 2003
This essay reviews literature on the theoretical views underlying the selection of activities for classrooms of English literature teaching in EFL context.
Yazid Basthomi
doaj   +3 more sources

Childhood Hermeneutics and the Uniqueness of the Aesthetic Reading of Children’s Literature

open access: yesEncyclopaideia
The purpose of this paper is to reflect on the uniqueness of the aesthetic reading of children’s literature and child hermeneutics as foundations for reading education.
Stefania Carioli
doaj   +1 more source

Towards critical literacy : literature and teachers' reactions to reader-response theories : a thesis presented in fulfilment of the requirements for the degree of Master of Arts in Second Language Teaching at Massey University [PDF]

open access: yes, 1999
Much poststructuralist literary theory, in particular that derived from reader-response theories, points to the need for the development in readers of a more critical literacy.
Brown, R. A. Julie
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Role of Implied Reader in the Realm of Literary Criticism [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
This article aims to examine the process of text reading and understanding, based on the concept of implied reader, for the definition of which, we have synthesized herein the seemingly antithetical methods of ‘authorial’ and ‘reader-oriented’ criticism.
Hossein Safi Pirlooje
doaj  

Psychoanalytic Literary Criticism: Using Holland’s DEFT Model as a Reader Response Tool in the Language Classroom

open access: yesLanguage and Psychoanalysis, 2013
Language students tend to struggle with literature because they find psychological and socio-cultural implications embedded in literary texts difficult to understand and discuss (Kramsch, 1996).
Lubie Grujicic-Alatriste
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

«Reader! Bruder!»: The Rhetoric of Narration and the Rhetoric of Reading

open access: yesBetween, 2014
The paper deals with the relation of power established by narrative texts, exploring the many-sided field of articulation among the related subjects: the narrator as a subject of power, the text as a rhetorical device, and the reader as an ultimate ...
Federico Bertoni
doaj   +1 more source

Industrialisation and Human Social Development: Charles Dickens’ Hard Times as a Conscience to Sciences [PDF]

open access: yes, 2018
This critical research work aims at investigating on Dickens\u27s outstanding academy which is incharge of all boys\u27 and girls\u27 education in the Britain\u27s 19th century.
YEKINI, I. (Ibrahim)
core  

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