Results 121 to 130 of about 3,533,611 (280)

Services of a private office for a teacher and a student of the Siberian Federal University Scientific Library

open access: yesБиблиосфера, 2015
The paper analyzes information requirements and interests of higher school library users. It presents services of a private office for a student, a teacher and administrative personnel of higher education institution available at the Siberian Federal ...
R. A. Baryshev, O. I. Babina
doaj  

Analisis Suggestopedia Kenyamanan Ruang Perpustakaan dalam Meningkatkan Daya Konsentrasi Pembaca di Perpustakaan Monumen Pers Nasional Surakarta

open access: yesJurnal Pustaka Ilmiah
This research aims to analyze the implementation of the suggestopedia theory in increasing the concentration of readers at the National Press Monument Library in Surakarta. This research uses a qualitative descriptive study method through the concepts of
Dian Muhammad Rifai   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Gothic Chapbooks and the Urban Reader [PDF]

open access: yes, 2010
This article discusses some principles of Gothic bluebooks and chapbooks. It emphasizes the idea that because of its derivative nature and lack of artistic sophistication, chapbooks were ignored by urban readers. It outlines the views of several scholars,
Hoeveler, Diane
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Operation of an electron-bombardment ion source using various gases [PDF]

open access: yes
An electron-bombardment ion thruster of the SERT 2 type was operated with xenon, krypton, argon, neon, nitrogen, helium, and carbon dioxide. The discharge performance with xenon, krypton, and argon was similar to that obtained previously with mercury ...
Byers, D. C., Reader, P. D.
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Research on a non-destructive fluidic storage control device [PDF]

open access: yes
Fluidic memory device with associated fluidic alpha numerical ...
Ho, S. K., Reader, T. D.
core   +1 more source

Readers' Copyright

open access: yes, 2017
This essay is part of a project intended to help reclaim copyright for readers, listeners, and viewers. A system of copyright protection makes little sense unless it is designed to encourage the use and enjoyment of the works it induces authors to create and publishers to disseminate. I argue that a clear-eyed examination of copyright's history reveals
openaire   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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