Results 121 to 130 of about 1,154,560 (308)
Cosey Complex Reader
, 2010 Mo Throp contributed to this publication.
COSEY COMPLEX Reader was produced as a discursive intervention produced in the ICA's Reading Room in the weeks leading up to COSEY COMPLEX at ICA, London on 27 March ...Throp, Mocore Action to protect the independence and integrity of global health research
BMJ Global Health, 2019 David Sanders, Lu Gram, Benjamin Tsofa, Johanne Sundby, Tolib Mirzoev, Kristine Bærøe, Ole Frithjof Norheim, Ejemai Eboreime, Valéry Ridde, Kristine Husøy Onarheim, Emily Mendenhall, Vladimir S Gordeev, Tanya Doherty, Stephen Taylor, David Peters, Shariful Islam, Madhukar Pai, Elysée Nouvet, Francesca L Cavallaro, Shafiu Mohammed, Sassy Molyneux, Karl Blanchet, Janice E Graham, Kayvan Bozorgmehr, David McCoy, Joel Lexchin, Anna-Karin Hurtig, Asha George, Rachel Chapman, Loveday Penn-Kekana, Katerini T Storeng, Dina Balabanova, Veronique Filippi, Sidsel Roalkvam, Grace Akello, Melissa Parker, Jennifer Palmer, Ibukun Abejirinde, Babatope Adebiyi, Clara Affun-Adegbulu, Jhon Álvarez Ahlgren, Ayesha Ahmad, Sameh Al-Awlaqi, Zongo Aloys, Gianna Gayle Amul, Muhammad Asaduzzaman, Akeza Awealom Asgedom, Bouchra Assarag, Nicole Atchessi, Salla Atkins, Okikiolu Badejo, Bailah Molleh, Alessandra Bazzano, Dominique P Béhague, Uli Beisel, Loubna Belaid, Sarah Bernays, Shafi Bhuiyan, Olivia Biermann, Harriet Birungi, Astrid Blystad, Oriane Bodson, Emmanuel Bonnet, Shibaji Bose, Michelle Brear, Rochelle Burgess, Jens Byskov, Séverine Carillon, Sophie Chabeda, Clare Chandler, Francis F Chikuse, Juliana Iwu Chinwe, Beniamino Cislaghi, Svea Closser, Christopher J Colvin, Jenny Cresswell, Fabiana da Cunha Saddi, Judith Daire, Sarah Dalglish, Vincent de Brouwere, Jean-Pierre Olivier de Sardan, Thérèse Delvaux, Annabel Desgrées du Loû, Brahima A Diallo, Aïssa Diarra, Justin Dixon, Alexandre Dumont, Beth Engelbrecht, Susan Erikson, Adama Faye, Sara Fischer, Florence Fournet, Ashley M Fox, Joel Msafiri Francis, Lara Gautier, Lucy Gilson, Sarah Gimbel, Jeff Glenn, Unni Gopinathan, Christoph Gradmann, Giulia Greco, Karen Grepin, Anne Guichard, Pragya Tiwari Gupta, Viveka Guzman, Marte E S Haaland, Anna Häggblom, Amy Hagopian, Karin Hammarberg, Pascal Handschumacher, Katrina Hann, Marie Hasselberg, Natasha Howard, Sameera Hussain, Eleanor Hutchinson, Ezirim Idoteyin, Jennifer J Infanti, Rachel Irwin, Taufique Joarder, Preethi John, Ermel Johnson, Mira Johri, Judith Justice, Charles Kaboré, Kadidiatou Kadio, Matthieu Kamwa, Ann H Kelly, Nora Kenworthy, Sonja Kittelsen, Maren Olene Kloster, Emily Kocsis, Pratap Kumar, Arush Lal, Isabelle Lange, Heather Lanthorn, Frederic Le Marcis, Shelley Lees, Ann Louise Lie, Gojjam Limenih, Isabel Litwin-Davies, Charles Clarke Lodda, Knut Lönnroth, John Manton, Anatole Manzi, Mehr Manzoor, Robert Marten, Mitsuaki Matsui, Allan Mbewe, Esther Mc Sween-Cadieux, Linsey McGoey, Desmond McNeill, Claudio A Méndez, Karen Marie Moland, Zubia Mumtaz, Susan Fairley Murray, Devaki Nambiar, Erica Nelson, Claudia Nieto-Sanchez, Francis Obare, Vincent Okungu, Marit Tolo Østebø, Fatoumata Ouattara, Sachiko Ozawa, Ligia Paina, Rakesh Parashar, Elisabeth Paul, Koen Peeters, Cédric Pennetier, James Pfeiffer, Hanneke Pot, N S Prashanth, Robyn Preston, Antoine de Bengy Puyvallee, Annisa Rahmalia, Simon Reid-Henry, Daniela C Rodríguez, Maya Ronse, Emma Sacks, Oumar Mallé Samb, Eric Sarriot, Inger Brummenæs Scheel, Thomas Schwarz, Kerry Scott, Janet Seeley, Nadine Seward, Geordan Shannon, Jessica Shearer, Katharine Shelley, Kenneth Sherr, Jeremey Shiffman, Frédéric Simard, Neha S Singh, Werner Soors, Rusla Anne Springer, Adrienne Strong, Moses Tetui, Stephanie M Topp, Anne-Marie Turcotte-Tremblay, Chi-Chi Undie, Sara Van Belle, Godelieve Van Heteren, André Janse van Rensburg, Veena Sriram, Sridhar Venkatapuram, Bradley H Wagenaar, Lauren Wallace, David R Walugembe, Oghenebrume Wariri, Alan OBE Whiteside, Bereket Yakob, Scholastica Zakayo, Tony Zitti, Anthony Zwi +212 moredoaj +1 more sourceAdaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová +10 morewiley +1 more sourceLongitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay +15 morewiley +1 more sourceInterpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo +7 morewiley +1 more sourceProteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi +10 morewiley +1 more sourceClinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski +12 morewiley +1 more source
