Results 161 to 170 of about 1,806,462 (261)

Non-inferiority analysis of a fetal heart rate artificial intelligence algorithm to registered nurse assessment. [PDF]

Pregnancy (Hoboken)
Pardasani R, Vitullo R, Harris S, Becker KP, Yapici HO, Beard JW.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Deep Learning Quality Control for RECIST-Oriented Assessment: A Vision Transformer Predicts Inter-Reader Variability of Unidimensional Lesion Measurements on Contrast CT. [PDF]

Cancers (Basel)
Ibrahim A, Hammad A, Wang L, Yang H, Schwartz LH, Zhao B.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Deep-Inspiration Breath-Hold Strategy Improves Image Quality of Transthoracic Lateral Shoulder Radiography. [PDF]

Diagnostics (Basel)
Shu PW, Cheng QG, Wang Y, Feng PY, Shen YH, Sun P, Lei ZQ, Fu Q.   +7 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Impact of Regeneration on the Dosimetric Properties of LiF:Mg,Cu,P (MCP-N) Detectors. [PDF]

Sensors (Basel)
Gordon P, Matusiak K, Kłosowski M, Jung A.   +3 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

When You See Someone Clinging to a Rigid Paradigm, Do You Extend Your Hand, Do You Reach for a Hammer or Do You Walk Away?

Philosophical Inquiry in Education, 2007
A Gentle Reader
doaj  

Artificial Intelligence in Gallbladder Imaging: A Rapid Evidence Review and Exploratory Meta-Analysis of Diagnostic Performance and Reader Assistance. [PDF]

Cureus
Karan Chand Mohan Singh S, J J, Shiny E, I N, Mani S, K S.   +5 more
europepmc   +1 more source