Results 51 to 60 of about 3,533,611 (280)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
ACROSS, 2021 The problem of the contemporary writer is the range of his/her vocabulary and idiomatic phrases. In spite of the Romanian slang being so rich, the corresponding literature manifests a sort of deafness in this regard.
Felix NICOLAU, Prof. Habil.
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Transmedya Hikayeciliğinde Wattpad Örneği ve Okur Tercihlerine Yönelik Bir Araştırma
Online Academic Journal of Information Technology, 2018 Yeni medya dolayımıyla izleyici/kullanıcının, alımlama/okuma alışkanlıkları değişime uğramıştır. Yeni medyanın interaktif katılıma imkan tanımasıyla, alıcı medya içeriğini tüketen olmasının yanı sıra içeriği üreten, şekillendirebilen bir nitelik de ...
Kübra Güran Yiğitbaşı
doaj +1 more source
Review of research and development in fluid logic elements [PDF]
, 1967 Research and development in multistate fluid logic elements is reviewed in a historical and critical report. The report concludes that in the development of fluid amplifiers, there are elements with very high gain and poor switching speed, and other ...
Reader, T.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evaluation Criteria for Reader-to-Reader Anti-collision Protocols [PDF]
, 2012 Technical ...
Ferrero, Renato +3 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source