Results 51 to 60 of about 3,623,074 (328)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Unde 'ni' sunt argou-nauţii?

open access: yesACROSS, 2021
The problem of the contemporary writer is the range of his/her vocabulary and idiomatic phrases. In spite of the Romanian slang being so rich, the corresponding literature manifests a sort of deafness in this regard.
Felix NICOLAU, Prof. Habil.
doaj  

Evaluation Criteria for Reader-to-Reader Anti-collision Protocols [PDF]

open access: yes, 2012
Technical ...
Ferrero, Renato   +3 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Transmedya Hikayeciliğinde Wattpad Örneği ve Okur Tercihlerine Yönelik Bir Araştırma

open access: yesOnline Academic Journal of Information Technology, 2018
Yeni medya dolayımıyla izleyici/kullanıcının, alımlama/okuma alışkanlıkları değişime uğramıştır. Yeni medyanın interaktif katılıma imkan tanımasıyla, alıcı medya içeriğini tüketen olmasının yanı sıra içeriği üreten, şekillendirebilen bir nitelik de ...
Kübra Güran Yiğitbaşı
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

RNA m6A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/β-catenin signaling [PDF]

open access: gold, 2021
Yin Li   +9 more
openalex   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Globally Normalized Reader

open access: yes, 2017
Rapid progress has been made towards question answering (QA) systems that can extract answers from text. Existing neural approaches make use of expensive bi-directional attention mechanisms or score all possible answer spans, limiting scalability.
Miller, John, Raiman, Jonathan
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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