Results 51 to 60 of about 1,806,462 (261)
A novel m6A reader Prrc2a controls oligodendroglial specification and myelination
Cell Research, 2018 While N6-methyladenosine (m6A), the most abundant internal modification in eukaryotic mRNA, is linked to cell differentiation and tissue development, the biological significance of m6A modification in mammalian glial development remains unknown. Here, we
Rong-Rong Wu +20 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Definitions, 2020 Inleiding Het is lang zo geweest dat vrije beoefenaren zoals artsen, accountants en advocaten, hun beroep als zelfstandige uitoefenden. De persoonlijke beroepsuitoefening stond voorop want het ging om het aanwenden van de intellectuele capaciteiten van ...
Raden van Commissarissen +1 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
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Transmedya Hikayeciliğinde Wattpad Örneği ve Okur Tercihlerine Yönelik Bir Araştırma
Online Academic Journal of Information Technology, 2018 Yeni medya dolayımıyla izleyici/kullanıcının, alımlama/okuma alışkanlıkları değişime uğramıştır. Yeni medyanın interaktif katılıma imkan tanımasıyla, alıcı medya içeriğini tüketen olmasının yanı sıra içeriği üreten, şekillendirebilen bir nitelik de ...
Kübra Güran Yiğitbaşı
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The Plant Cell, 2018 A YTH domain protein acts as a reader of m6A mRNA modifications, thereby playing crucial roles in trichome branching, likely by acting on mRNAs in the cytosol. Methylations at position N6 of internal adenosines (m6As) are the most abundant and widespread
Jérémy Scutenaire +7 more
semanticscholar +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
ACROSS, 2021 The problem of the contemporary writer is the range of his/her vocabulary and idiomatic phrases. In spite of the Romanian slang being so rich, the corresponding literature manifests a sort of deafness in this regard.
Felix NICOLAU, Prof. Habil.
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