Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Reader Response: Oral Anticoagulants and the Risk of Dementia in Patients With Nonvalvular Atrial Fibrillation: A Population-Based Cohort Study. [PDF]
Neurology, 2023 Feng Q.
europepmc +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Reader Response: <i>D313Y</i> Variant in Fabry Disease: A Systematic Review and Meta-analysis. [PDF]
Neurology, 2023 Lackova A +4 more
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Літературна критика Стенлі Фіша: від афективної стилістики до теорії «інтерпретаційних спільнот» [PDF]
, 2014 Стенлі Ю.Фіш (1938 - ) як представник теорії читацького відгуку у США (кінець 1960-х – поч. 80-х) один з перших кинув виклик авторитетності принципіальної доктрини «нової критики» – т.зв. «афективної помилки».
Анісімова, Людмила Вікторівна
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Reader Response: Microembolism and Other Links Between Migraine and Stroke: Clinical and Pathophysiologic Update. [PDF]
Neurology, 2023 Scutelnic A, Jung S, Schankin CJ.
europepmc +1 more source
, 2006 In January 2006, this Journal published an article that set forth the social institutional argument for man/woman marriage, demonstrated how that argument is a sufficient response to all constitutional attacks leveled at the laws sustaining that social ...
Stewart, Monte Neil
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Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Reader Response: Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant. [PDF]
Neurology, 2023 Wolfe J, Siegler JE.
europepmc +1 more source