Results 161 to 170 of about 10,847,883 (304)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Innovation in Humanitarian Action: Editors’ Introduction

open access: yesJournal of Humanitarian Affairs, 2020
Tanja R. Müller, Gemma Sou
doaj   +1 more source

“He inspired others to change his world”: An Exploration of Taking Action Through Reading and Writing

open access: yesWOW Stories, 2011
This vignette focuses on how children can learn to take action in their communities after critically reading and discussing an Identity Text Set. By providing background knowledge and global literature, students can view themselves as global citizens ...
Jenna Loomis
doaj  

No wisdom in the crowd: genome annotation at the time of big data - current status and future prospects [PDF]

open access: yes, 2018
Science and engineering rely on the accumulation and dissemination of knowledge to make discoveries and create new designs. Discovery-driven genome research rests on knowledge passed on via gene annotations.
Danchin, Antoine
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Вплив філософії прагматизму на літературознавство США: від транзакційної теорії Л.М. Розенблатт до «неопрагматизму» С. Фіша [PDF]

open access: yes, 2015
У статті досліджено вплив філософії прагматизму на літературознавство США, зокрема на літературні теорії двох відомих представників теорії читацького відгуку – Луїзи Мішель Розенблатт (1904-2005) і Стенлі Фіша (1938-).
Анісімова, Людмила Вікторівна
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

History Matters: Grade Six Students Reflect on the Effects of War

open access: yesWOW Stories, 2013
This vignette focuses on ways to integrate global literature into a sixth grade classroom. Through a unit focused on World War II, students were introduced to a variety of different countries and people during that era and critically reflected on what ...
Krista Jiampetti
doaj  

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