Results 71 to 80 of about 1,830,580 (292)

The Relevance of the Reading Process in the Context of Estonian Literary Criticism

open access: yesInterlitteraria, 2020
The importance of the reading experience has been accepted in literary studies ever since the advent of reading-response theories in the 1970s-1980s. Several notable scholars have stressed that meaning is created through the interaction between reader ...
Susanna Soosaar
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

One text, many stories: The (ir)relevance of reader- response criticism for apocryphal literature in the Septuagint

open access: yesHTS Teologiese Studies/Theological Studies, 2012
This article investigated the value of reader-response theory for the reading of apocryphal texts in the Septuagint. The groundbreaking work on reader-response theory developed by Wolfgang Iser in his book The Act of Reading: A Theory of Aesthetic ...
S. Philip Nolte
doaj   +3 more sources

“An Unexpected Sound”: Recognizing Diverse Voices in Postcolonial Literary Interpretation

open access: yesIAFOR Journal of Literature & Librarianship, 2012
This article explores expectations about the ways in which readers from each side of the colonial/colonized divide might approach texts. Pedagogical articles about world and postcolonial literature frequently classify readers in one of two categories ...
Joanne Nystrom Janssen
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

First Grade Explorations of Global Literature about the Middle East

open access: yesWOW Stories, 2011
This vignette discussing global children's literature used to promote global awareness and sensitivity within a first grade classroom through use of critical group discussions.
Jackie Iob
doaj  

The Online Response to the Two Polish Translations of The Wee Free Men by Terry Pratchett

open access: yesPółrocznik Językoznawczy Tertium, 2017
The online community of science fiction and fantasy fans constitutes a rich source of material for analysing reader response to translations as its members often reflect not only on the books they read but also on the quality of their translations. The
Katarzyna Dziemian
doaj   +1 more source

The Construction of Muslim Terrorism in the Kingdom Movie 2007 Directed by Peter Berg: A Reception Theory [PDF]

open access: yes, 2015
This study belongs to the literary study. This study analyzes the construction of Muslim terrorism based on reader response reflected in The Kingdom Movie (2007).
, Dr. M. Thoyibi, M.S   +2 more
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