Results 121 to 130 of about 1,775,381 (345)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
"Cities of Readers" at IMC Leeds 2017
, 2017 This year two members of "Cities of Readers" presented papers at the International Medieval Congress 2017 in Leeds: Sabrina Corbellini presented a paper entitled Spiritual Landscapes in Late Medieval Florence: Letters and Networks in the session ...
Margriet Hoogvliet
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Reading in the digital age: using electronic books as a teaching tool for beginning readers [PDF]
, 2012 This study investigated the eBook reading experiences of eight grade 1 students. Eight students were given ten 25-minute sessions with the software programs over 15 weeks.
Katia Ciampa
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Álabe, 2013 En esta aportación tratamos de justificar por qué existe la necesidad de formar lectores críticos en la sociedad dinámica y cambiante del siglo XXI. Considerando que las obras distópicas contribuyen a la conformación de dicha tipología de lector, en esta
Amando López Valero +1 more
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Catching Readers Before They Fall Supporting Readers Who Struggle, K-4
Every teacher of reading plays a vital role in helping to catch those readers for whom learning to read does not come easily. Through examples from both adults and children, the authors explain and describe the complex integrated network of strategies ...
Keier, Katie., Johnson, Pat.
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The Heroine as Reader, the Reader as Heroine: Jennifer Crusie’s Welcome to Temptation
Journal of Popular Romance Studies, 2012 This article examines Jennifer Crusie’s Welcome to Temptation (2000) as a response to academic accounts of the nature and value of reading the popular romance from the 1980s and 1990s and as an anticipation of later, more positive accounts of the ...
Kate Moore, Eric Murphy Selinger
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