Results 131 to 140 of about 1,775,381 (345)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Children as Readers in Children's Literature : the Power of Texts and the Importance of Reading
, 2015 We are fascinated by text and we are fascinated by reading. Is this because we are in a time of textual change? Given that young people always seem to be in the vanguard of technological change, questions about what and how they read are the subject of ...
core +3 more sources
БІБЛІОТЕЧНА ДІЯЛЬНІСТЬ ШЕПЕТІВСЬКОГО АРХАНГЕЛО-МИХАЙЛІВСЬКОГО БРАТСТВА У 90-х рр. ХІХ ст. [PDF]
Storìnki Istorìï, 2013 Based on historical sources and scientific literature, this article obsetves formation and the development of libraries of Archangel-Michael church orthodox fraternity in the town of Shepetivka of Zaslavsky district of Volyn province at the end of XIX ...
О. В. Сажок
doaj
, 2004 The paper develops the functional dimension of the procedural model that explains how a digital literary work differs in its own from a classical print work. Generally the differences are considered as the introduction of the interactivity and the hypertextual dimension.
openaire +1 more source
Serving Teens through Readers' Advisory
Getting teens to read for fun is the ultimate challenge, yet research shows that it improves skills in grammar and spelling while expanding vocabularies.
Booth, Heather.
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 1935 Third level Royal Reader comprising illustrated short prose pieces and poems with pronunciation guides and simple definitions. Includes questions and writing exercises. Used in the schools of Newfoundland and Labrador from the 1870's until well into the
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source