From shadows to signals: exploring the strengths and limitations of artificial intelligence in breast cancer lesion detection on screening mammograms compared to radiologists and radiology trainees. [PDF]
Trieu PDY +6 more
europepmc +1 more source
Second level Royal Reader with short prose pieces and poems designed to stimulate interest and an enthusiasm for reading. Includes pronunciations and simple definitions of new words. Questions on content follow each lesson.
core
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Background parenchymal enhancement in ultrafast MRI: Inter-reader agreement before and after training, and correlations with prognostic factors of breast cancer. [PDF]
Yamaguchi K +8 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Impact of Artificial Intelligence Assistance on Radiologist Performance in CT-Based Pulmonary Nodule Detection: A Systematic Review and Meta-Analysis of Detection Accuracy Studies. [PDF]
Singh V +4 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Psychological mechanisms through which classical tang and song poetry moves contemporary readers: a qualitative study based on the aesthetics of reception. [PDF]
He Q, Zhang R, Liang Z.
europepmc +1 more source

