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The Readers' Advisory Guide to Horror

As both an introductory guide for librarians just dipping their toes into the brackish water of scary fiction, as well as a fount of new ideas for horror-aware reference staff, Spratford's book is infernally appropriate.Intro -- Title Page -- Copyright ...
Siegel Spratford, Becky.
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The Cover of (<i>The Rolling Stone</i>) CASE. [PDF]

CASE (Phila)
Sorrell VL.
europepmc   +1 more source

E-readers and struggling middle school readers

, 2016
Research is emerging to understand how technology affects student attitudes towards reading. Research on the influence of e­-books on struggling adolescent readers, however, is limited.
Hendrickson, Abigail L.
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

AI Decision Support for Emergency Triage of Large Vessel Occlusion Using Noncontrast Computed Tomography: Systematic Review and Bayesian Diagnostic Test Accuracy Network Meta-Analysis. [PDF]

J Med Internet Res
Zhou H, Liu L, Fu B, Cao B, Ma J, Yang K, Bao Y, Yang F, Lian X.   +8 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Editorial Expression of Concern: Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis. [PDF]

BMC Neurosci
Hunter K, Hölscher C.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Fluent but not fail-safe: machine-translated radiology reports still need expert review. [PDF]

Eur Radiol Exp
Seibold C, Leichenich T, Stein P, Atsiatorme E, Kliesch P, Sevim GA, Trauth P, Kremer A, Bischoff A, Kauczor HU, Fink MA.   +10 more
europepmc   +1 more source