Results 31 to 40 of about 344,717 (292)

School Readiness [PDF]

Pediatrics, 2008
School readiness includes the readiness of the individual child, the school's readiness for children, and the ability of the family and community to support optimal early child development. It is the responsibility of schools to be ready for all children at all levels of readiness.
openaire   +2 more sources

Acute and Delayed Effects of Stress Eliciting Post-Traumatic Stress-Like Disorder Differentially Alters Fecal Microbiota Composition in a Male Mouse Model

Frontiers in Cellular and Infection Microbiology, 2022
The association between the shift in fecal resident microbiome and social conflicts with long-term consequences on psychological plasticity, such as the development of post-traumatic stress disorder (PTSD), is yet to be comprehended.
Allison Hoke, Allison Hoke, Nabarun Chakraborty, Aarti Gautam, Rasha Hammamieh, Marti Jett   +5 more
doaj   +1 more source

Are Acute Stroke-Ready Hospitals Ready? [PDF]

Stroke, 2013
See related article, p 3382. In 2005, an American Stroke Association Task Force report described the rationale and components of an integrated stroke system of care extending from primordial prevention through primary prevention, acute management, secondary prevention, and poststroke rehabilitation and recovery.1 The principle that optimal patient ...
openaire   +2 more sources

Nexus of Digital Organizational Culture, Capabilities, Organizational Readiness, and Innovation: Investigation of SMEs Operating in the Digital Economy

Sustainability, 2021
This current study was conducted in order to develop a digital innovation model based on the digital organizational culture, digital capability, and organizational readiness.
Zhang Zhen, Zahid Yousaf, M. Radulescu, Muhammad Yasir   +3 more
semanticscholar   +1 more source

Technology readiness: a meta-analysis of conceptualizations of the construct and its impact on technology usage

Journal of the Academy of Marketing Science, 2019
The technology readiness (TR) index aims to better understand people’s propensity to embrace and use cutting-edge technologies. The initial TR construct considers four dimensions—innovativeness, optimism, insecurity, and discomfort—that collectively ...
Markus Blut, Cheng Wang
semanticscholar   +1 more source

The effect of the online flipped classroom on self-directed learning readiness and metacognitive awareness in nursing students during the COVID-19 pandemic

BMC Nursing, 2022
Background The COVID-19 pandemic has initiated digital developments in higher education while closing in-person university classes. As this crisis continues, the need to revive virtual learning opportunities was seriously felt.
Safoura Khodaei, S. Hasanvand, Mohammad Gholami, Y. Mokhayeri, M. Amini   +4 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Sex differences in treatment outcomes among U.S. service members with comorbid PTSD and MDD

BMC Psychology
Background Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are prevalent and deleterious conditions that commonly co-occur among service members.
Lisa H. Glassman, Nicholas P. Otis, Alexander C. Kline, W. Michael Hunt, Kristen H. Walter   +4 more
doaj   +1 more source

Severe, short-term sleep restriction reduces gut microbiota community richness but does not alter intestinal permeability in healthy young men

Scientific Reports, 2023
Sleep restriction alters gut microbiota composition and intestinal barrier function in rodents, but whether similar effects occur in humans is unclear.
J. Philip Karl, Claire C. Whitney, Marques A. Wilson, Heather S. Fagnant, Patrick N. Radcliffe, Nabarun Chakraborty, Ross Campbell, Allison Hoke, Aarti Gautam, Rasha Hammamieh, Tracey J. Smith   +10 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source