Results 31 to 40 of about 1,487,886 (323)

A weak-constraint 4DEnsembleVar. Part I: formulation and simple model experiments

open access: yesTellus: Series A, Dynamic Meteorology and Oceanography, 2017
4DEnsembleVar is a hybrid data assimilation method which purpose is not only to use ensemble flow-dependent covariance information in a variational setting, but to altogether avoid the computation of tangent linear and adjoint models.
Javier Amezcua   +2 more
doaj   +1 more source

COVID-19-Associated Thrombotic Thrombocytopenic Purpura: A Case Report and Systematic Review

open access: yesHematology Reports, 2022
Introduction: The proliferation of literature regarding the COVID-19 pandemic has served to highlight a wide spectrum of disease manifestations and complications, such as thrombotic microangiopathies.
Haseeb Chaudhary   +8 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Severe anion gap metabolic acidosis associated with initiation of a very low-carbohydrate diet

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2019
Low carbohydrate diets have been popularized as an effective solution for weight loss. Although rare, life-threatening anion gap metabolic acidosis has been reported in patients on these diets.
Sijan Basnet   +5 more
doaj   +1 more source

Improvements in Forecasting Intense Rainfall: Results from the FRANC (Forecasting Rainfall Exploiting New Data Assimilation Techniques and Novel Observations of Convection) Project

open access: yesAtmosphere, 2019
The FRANC project (Forecasting Rainfall exploiting new data Assimilation techniques and Novel observations of Convection) has researched improvements in numerical weather prediction of convective rainfall via the reduction of initial condition ...
Sarah L. Dance   +22 more
doaj   +1 more source

Reducing Solid-State Drive Read Latency by Optimizing Read-Retry (Extended Abstract) [PDF]

open access: yesarXiv, 2020
3D NAND flash memory with advanced multi-level cell techniques provides high storage density, but suffers from significant performance degradation due to a large number of read-retry operations. Although the read-retry mechanism is essential to ensuring the reliability of modern NAND flash memory, it can significantly increase the read latency of an ...
arxiv  

Quantum reading capacity: General definition and bounds [PDF]

open access: yesIEEE Transactions on Information Theory, vol. 65, no. 11, pages 7566--7583, November 2019, 2017
Quantum reading refers to the task of reading out classical information stored in a read-only memory device. In any such protocol, the transmitter and receiver are in the same physical location, and the goal of such a protocol is to use these devices (modeled by independent quantum channels), coupled with a quantum strategy, to read out as much ...
arxiv   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Distributed transactional reads: the strong, the quick, the fresh \& the impossible [PDF]

open access: yesACM. 2018 ACM/IFIP/USENIX International Middleware Conference, Dec 2018, Rennes, France. ACM, 2018 ACM/IFIP/USENIX International Middleware Conference, pp.14, 0018, Proceedings of 2018 ACM/IFIP/USENIX International Middleware Conference. http://2018.middleware-conference.org, 2018
This paper studies the costs and trade-offs of providing transactional consistent reads in a distributed storage system. We identify the following dimensions: read consistency, read delay (latency), and data freshness. We show that there is a three-way trade-off between them, which can be summarised as follows: (i) it is not possible to ensure at the ...
arxiv   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

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