Results 91 to 100 of about 5,397,966 (284)

Do Students Correctly Estimate Their Reading Ability? A Study of Stockholm Students in Grades 3 and 8

open access: yes, 2011
Data from a survey in Stockholm are used to look at differences between how students’ self-concepts and self-efficacy relate to actual reading skills, differences between how boys and girls estimate their reading, and differences between how older and ...
Ulf Fredriksson   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Is Statistical Learning Ability Related to Reading Ability, and If So, Why?

open access: yes, 2018
Previous studies found a relationship between performance on statistical learning (SL) tasks and reading ability and developmental dyslexia. Thus, it has been suggested that the ability to implicitly learn patterns may be important for reading ...
Schmalz, X   +11 more
core   +1 more source

Effectiveness of Mnemonic Instruction in Enhancing of Reading Ability Among Grade Three Learners with Dyslexia in Two Primary Schools in South Africa

open access: yesAcademicus International Scientific Journal
The current study assessed the efficacy of the mnemonic instruction (MI) in enhancing reading abilities among grade three learners with reading disability in two government schools (grade R to 7) in Mpumalanga, South Africa.
Lilian Zindoga, Peter JO Aloka
doaj   +1 more source

Analysis of ESP university students’ reading strategy awareness [PDF]

open access: yesIbérica, 2008
The research literature on metacognitive awareness of reading strategies indicates the need to increase our understanding of readers’ metacognitive knowledge about reading and reading strategies so that individuals develop into active, constructively ...
Ana Cristina Lahuerta Martínez
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Emergent Attentional Bias Toward Visual Word Forms in the Environment: Evidence From Eye Movements

open access: yesFrontiers in Psychology, 2018
Young children are frequently exposed to environmental prints (e.g., billboards and product labels) that contain visual word forms on a daily basis. As the visual word forms in environmental prints are frequently used to convey information critical to an
Jing Zhao   +11 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Reading-related skills in earlier- and later-schooled children [PDF]

open access: yes, 2011
We investigate the effects of age-related factors and formal instruction on the development of reading-related skills in children aged four and seven years. Age effects were determined by comparing two groups of children at the onset of formal schooling;
Carroll, Julia M.   +3 more
core   +1 more source

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