Results 91 to 100 of about 92,409 (301)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Uniplanar nystagmus associated with perceptual and cognitive visual dysfunction due to presumed focal ischemic occipital cortical atrophy: a missed diagnosis and new observation [PDF]
, 2012 Uniplanar nystagmus has been described in relation to pathology of the brain stem, retina, optic nerve, sensory visual deprivation, periventricular leucomalacia, and drug toxicity.
Dorris, Liam +2 more
core +3 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A follow-up study of 100 reading disability cases, now adults, who were associated with the Boston University Education Clinic between 1936-1948 [PDF]
, 1951 Thesis (Ed.M.)--Boston ...
Frost, Ruth E. +3 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Clinical Ophthalmology, 2017 Sri Ganesh, Sheetal Brar, Archana PawarNethradhama Superspeciality Eye Hospital, Bangalore, Karnataka, India Purpose: To study the long-term visual and refractive outcomes and evaluate patient satisfaction after bilateral implantation of trifocal ...
Ganesh S, Brar S, Pawar A
doaj
Visual rehabilitation via microperimetry in patients with geographic atrophy: a pilot study
International Journal of Retina and Vitreous, 2017 Background Age-related macular degeneration (AMD) is the leading cause of blindness in the western world. As a consequence of AMD, patients develop structural damage that comprises the fovea and subsequently present loss of central vision, low visual ...
Juan Abel Ramírez Estudillo +5 more
doaj +1 more source
Questions and Answers About Blindness and Vision Impairments in the Workplace and the Americans with Disabilities Act [PDF]
, 2005 The Americans with Disabilities Act (ADA) is a federal law that prohibits discrimination on the basis of disability. Title I of the ADA makes it unlawful for any employer to discriminate against a qualified applicant or employee because of a disability ...
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
‘It’s too late’. Is it really? Considerations for amblyopia treatment in older children [PDF]
, 2019 In recent years, media coverage has demonstrated instances in which families of children aged 7 and older, newly diagnosed with strabismic and/or anisometropic amblyopia through community eyecare services, were told it was ‘too late’ for their child to ...
Apt L +9 more
core +1 more source