Results 81 to 90 of about 92,937 (285)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of levodopa and deep brain stimulation on visual impairments in Parkinson’s disease

Clinical Parkinsonism & Related Disorders
Background: Parkinson’s disease (PD) often causes visual changes that impair visuospatial processing, reading speed, and contrast acuity, impacting patients’ quality of life.
Sana Aslam, Markey Olson, Melissa Kovacs, Pireh Ansari, Amputch Karukote, Justine Chan, Shadi Barbu, Sydney Felsen, Holly A. Shill, Charles H. Adler   +9 more
doaj   +1 more source

Effect of Myopic Undercorrection on Habitual Reading Distance in Schoolchildren: The Hong Kong Children Eye Study

Ophthalmology and Therapy, 2022
Introduction This study aimed to evaluate the habitual reading distance among non-myopic children and also myopic children with undercorrection and with full correction.
Shu Min Tang, Xiu Juan Zhang, Yu Meng Wang, Yuzhou Zhang, Lok Man Wong, Hei-Nga Chan, Bi Ning Zhang, Wai Kit Chu, Ka Wai Kam, Alvin L. Young, Clement C. Tham, Li Jia Chen, Amanda N. French, Kathryn A. Rose, Chi Pui Pang, Jason C. Yam   +15 more
doaj   +1 more source

Electrical stimulation of visual cortex can immediately improve spatial vision [PDF]

, 2016
Published in final edited form as:Curr Biol. 2016 July 25; 26(14): 1867–1872. doi:10.1016/j.cub.2016.05.019.SUMMARY We can improve human vision by correcting the optics of our lenses [1, 2, 3].
McClenahan, Laura J., Reinhart, Robert M.G., Woodman, Geoffrey F., Xiao, Wenxi   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

When Computer Vision Gazes at Cognition [PDF]

, 2014
Joint attention is a core, early-developing form of social interaction. It is based on our ability to discriminate the third party objects that other people are looking at.
Gao, Tao, Harari, Daniel, Tenenbaum, Joshua, Ullman, Shimon   +3 more
core   +1 more source

‘It’s too late’. Is it really? Considerations for amblyopia treatment in older children [PDF]

, 2019
In recent years, media coverage has demonstrated instances in which families of children aged 7 and older, newly diagnosed with strabismic and/or anisometropic amblyopia through community eyecare services, were told it was ‘too late’ for their child to ...
Apt L, Berry C, College of Optometrists, Davis H, Levi DM, Price A, Reddy MA, Royal College of Ophthalmologists, Simmers AJ, West S   +9 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Investigating age related changes in taste and affects on sensory perceptions of oral nutritional supplements [PDF]

, 2010
Background: sip feeds are oral nutritional supplements (ONSs) that are commonly prescribed to malnourished patients to improve their nutritional and clinical status.
Arvidson, BAPEN, BAPEN, Bradley, British Standard Method for Sensory Analysis of Food, Chen, Clara Law, De Araujo, De Graaf, Donald Mottram, Elia, Elia, Fukunaga, Gosney, Kremer, Kremer, Lisa Methven, Margot Gosney, Mattes, McWhirter, Millen, Milne, Mojet, Mojet, NICE. National Institute for Health and Clinical Excellence, ONS, Orla Kennedy, Ralph, Sedwards, Stratton, Sugimoto, Wardwell, Wysocki   +32 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source