Results 81 to 90 of about 93,418 (279)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Reading deficits in diabetic patients treated with panretinal photocoagulation and good visual acuity [PDF]

open access: yesActa Ophthalmologica, 2019
AbstractPurposePatients with proliferative diabetic retinopathy (PDR) treated with panretinal photocoagulation (PRP) can have abnormal visual functioning that may be missed by Snellen visual acuity alone. We investigated reading deficits in patients treated with PRP for PDR using the Minnesota reading (MNREAD) test.MethodsThirty patients treated with ...
Amro Omari   +2 more
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Visual performance in cataract patients with low levels of postoperative astigmatism: full correction versus spherical equivalent correction

open access: yesClinical Ophthalmology, 2012
Robert P Lehmann1, Diane M Houtman21Lehmann Eye Center, Nacogdoches, TX, 2Alcon Research Ltd, Fort Worth, TX, USAPurpose: To evaluate whether visual performance could be improved in pseudophakic subjects by correcting low levels of postoperative ...
Lehmann RP, Houtman DM
doaj  

An analysis of the relationships between speech and reading abilities of four hundred and twenty-five first grade children. [PDF]

open access: yes, 1952
Thesis (Ed.M.)--Boston ...
Dumbleton, Charles F.   +6 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Factors affecting reading speed in patients with diabetic macular edema treated with laser photocoagulation. [PDF]

open access: yesPLoS ONE, 2014
PURPOSE: To study the factors that may affect reading speed in patients with diabetic macular edema previously treated with laser photocoagulation. METHODS: Consecutive patients with type II diabetes treated with laser photocoagulation for diabetic ...
Elizabeth Pearce   +2 more
doaj   +1 more source

Visual acuity standards for driving [PDF]

open access: yes, 2015
This paper reviews the current visual acuity standards for UK drivers. These standards have changed in recent years such that car drivers (Group 1) now have two standards to meet: reading a number plate at 20m, and achieving an acuity of 6/12.
Latham, Keziah, Rae, Sheila M.
core  

The effect of visual impairment on quality of life of children aged 3-16 years [PDF]

open access: yes, 2010
Background: It is well known that visual impairment (VI) has a detrimental effect on Quality of Life (QoL) in adults. Little is known about the effects of VI in childhood. Aims: To evaluate the effects of VI on QoL of children.
Chadha, R. K., Subramanian, A.
core   +3 more sources

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