Results 31 to 40 of about 318,995 (261)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Book covers are often the first component seen before a reader engages with a book’s contents; therefore, careful consideration is given to the text and image features that constitute their design.
Kirren Chana +6 more
doaj +1 more source
FACTORES MOTIVACIONALES Y DE CAPITAL CULTURAL QUE INCIDEN EN EL COMPORTAMIENTO LECTOR EN ESTUDIANTES MEXICANOS DE NIVEL MEDIO SUPERIOR DE DIFERENTE ESTRATO SOCIAL [PDF]
The objective was to determine to what extent motivational variables and those of cultural capital influence two dimensions of reading behavior (academic and non academic) in students from two different social strata (low and medium).The sample consisted
Mújica Sarmiento, Alejandro +2 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The antecedents of reading behavior in university libraries: a meta-analysis
IntroductionAlthough university libraries have become important places for readers to improve their literacy, acquire knowledge, and conduct academic research, however, scholars still have limited understanding of the antecedents of reading behavior ...
Ximei Zhao, Zhihong Li
doaj +1 more source
Today’s reading specialists are faced with students who not only present reading problems but, the likelihood of behavior problems. Thus, reading specialists must be prepared to implement behavior management strategies that de-escalate these ...
Keshona T. Beasley +1 more
doaj +1 more source
Reading is a popular leisure activity for children, teenagers, and adults. Several theories agree that reading might improve social cognition, but the empirical evidence remains tentative, with research on adolescents especially lacking.
Jan Lenhart +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

