Results 61 to 70 of about 1,820,887 (292)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Students’ Perceptions of Reading Circles in the EFL Classroom [PDF]

open access: yes, 2022
departmental bulletin ...
Kathryn, Mabe, 40464, Mabe, Kathryn
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Early Shelley: Vulgarisms, Politics, and Fractals [PDF]

open access: yes, 1997
Table of Contents About this Volume "Introduction: The Return of the 'Wild Boy'; or, Reading Early Shelley" - Neil Fraistat, University of Maryland   "Shelley Comes of Age: His Early Poems As an Editorial Experience" - Donald H.
Romantic Circles
core   +1 more source

Effects of literature circles activity on reading comprehension of L2 English learners: a meta-analysis

open access: yesHumanities & Social Sciences Communications
Literature circles have increasingly been utilized to enhance reading comprehension skills of second language (L2) English learners, yet the overall impact of this pedagogical approach remains unclear.
Lei Ma
doaj   +1 more source

Researches on The Accuracy of the DCMT Circle Reading System [PDF]

open access: yesSymposium - International Astronomical Union, 1993
The declinations of stars are determined by the circle micrometers on the meridian circle. The determined accuracy of declinations depends on the systematic accuracy of the micrometers. The DCMT (Danish Chinese Meridian Telescope) adopts photoelectric scanning micrometers as the circle reading system.
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Secularism, Cosmopolitanism, and Romanticism [PDF]

open access: yes, 2008
This volume of Romantic Circles Praxis Series includes an editor's introduction by Colin Jager, essays by Mark Canuel, Colin Jager, Paul Hamilton, and Bruce Robbins.  This volume begins to unpack the relationships among the three terms of its title.
Romantic Circles
core   +1 more source

Academic reading: fear and trembling or being and belonging?

open access: yesJournal of Learning Development in Higher Education
At the University of the West of England (UWE) Bristol, we are in the second year of a project to promote and improve reading skills. One part of our work has focused on embedding collaborative reading techniques within subjects to improve confidence in
Jane Saville, Tasha Cooper, Stephen Hunt
doaj   +1 more source

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