Results 91 to 100 of about 2,102,495 (293)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Tarnish\u27d with Ashes and Soot: A Classic Poem’s Dank Corners [PDF]

open access: yes, 2013
The legend is striking: Clement Clarke Moore, sitting with his children on a Christmas Eve in 1822, reading them a poem he has scrawled out that day, inspired by a winter shopping trip.
Rudy, John M.
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

The state of reading culture among secondary school students in Croatia: survey results

open access: yesKnjižnica, 2018
Purpose: Reinforcement and development of reading culture of secondary school students through theoretical and research section of the paper. The concept of reading culture among students of secondary schools is connected with the path of the book ...
Andreja Zubac
doaj   +1 more source

HUBUNGAN ANTARA KEGIATAN MENDONGENG DI PERPUSTAKAAN DENGAN BUDAYA BACA [PDF]

open access: yes, 2016
Penelitian ini dilatarbelakangi dengan rendahnya budaya baca siswa, serta kurang populernya kegiatan mendongeng di perpustakaan. Kegiatan mendongeng berfungsi untuk menarik siswa mencintai buku bacaan.
Quddus, Zayyin Abdul
core  

Psycho and The Orchestration of Anxiety [PDF]

open access: yes, 2010
Since its release in 1960, Alfred Hitchcock’s Psycho has entered the consciousness of our culture as have few other films. Its striking imagery, combined with its universally recognised score, has prompted a wealth of scholarly output.
Deutsch, Stephen
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

“Best read books” in Slovenian public libraries

open access: yesKnjižnica, 2008
The paper investigates hundred most borrowed books in public libraries in perspective of some trends in reading habits and general mission of public libraries.
Petra Jager
doaj   +1 more source

Reading a Quaker\u27s Book: Elizabeth Ashbridge\u27s Testimony of Quaker Literary Theory

open access: yes, 2014
Elizabeth Ash bridge offers one of the most striking transatlantic spiritual autobiographies of the eighteenth century. While historians and scholars alike have given careful attention to this now-canonical text, no one to date has yet positioned this ...
Tarter, Michele L.
core  

[Review of] Jeff Karem. The Romance of Authenticity: The Cultural Politics of Regional and Ethnic Literatures [PDF]

open access: yes, 2006
The romance of authenticity to which the title of Jeff Karem\u27s timely new study refers is the romance between the American reading public and the regional or ethnic writer who is viewed as providing an authentic cultural viewpoint, often to the ...
Lock, Helen
core   +1 more source

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