Results 71 to 80 of about 396,055 (267)
Knjižnica, 2016 Purpose: Written largely from a UK perspective, this paper presents a review of the literature regarding the nature of minority writing in the English language, and its supply, promotion and readership.
Briony Birdi
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Analysis of Factors Influencing Parental Knowledge Enhancement and the Development of Reading Culture in Children: A Phenomenological Study [PDF]
Taṣvīr-i salāmatBackground. Reading habits established in early childhood not only enhance cognitive and academic abilities but are also acknowledged as a powerful means to improve health literacy and enable future generations to make well-informed life choices ...
Seyed Jamal Haghirosadat Toranji +3 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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in the article, it is mentioned about raising reading culture in the education of the young generation. In addition, it is mentioned that the book is the main source for spiritual and moral nourishment, culture and language development in the society today.
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
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The Role of the Public Libraries of Kerman Region in Iran on Promoting Users\' Reading Culture [PDF]
تحقیقات اطلاعرسانی و کتابخانههای عمومی, 2016 Purpose: This research aims at the investigation of the role of public libraries of Kerman region in Iran, on promoting users' reading culture. Methodology: The research was done through a survey method.
hakimeh dehghani rayeni +2 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Вестник Тамбовского университета. Серия: Гуманитарные наукиImportance. The beginning of the process of interaction between Russian and French book cultures was laid by the era of the Europeanisation of Peter I. The Russian autocrat tirelessly sought to bring his country among the leading countries of the world ...
A. G. Topilsky
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
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