Results 71 to 80 of about 444,355 (314)
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The social construction of meaning : Reading Animal Farm in the classroom [PDF]
The novel, it has generally been assumed, was from its very beginnings a literary form designed to be read by solitary, silent individuals. One consequence of this assumption is that the class novel, read amid all the noise and sociality of the classroom,
Yandell, John
core
'A different kind of reading': the emergent literacy practices of a school-based graphic novel club
This paper explores the possibilities for pedagogy inherent in the reading practices which emerged from an extra-curricular graphic novel reading group set up in a Scottish secondary school.
Sabeti, Shari +2 more
core +1 more source
MODERN FICTION AS FACTOR OF STUDENTS’ READING CULTURE DEVELOPMENT
Nowadays there is an urgent need for the formation of students’ reading culture in a modern university. It is necessary to enhance the educational value of a book in students, who are losing their interest in reading.
Galyna Bilavych, Iryna Rozman
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Role of College English Textbooks in the Teaching of Culture in China [PDF]
The teaching of culture is one of the most important parts of English Language Teaching. It is unavoidable and necessary because English and culture are closely related and communication in English requires intercultural competence.
Jiang, Bo
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The thesis explores the reception of the works of the Scottish Enlightenment in provincial Scotland, broadly defined, aiming to gauge their diffusion in the libraries of private book collectors and 'public' book-lending institutions, and to suggest the ...
Towsey, Mark R. M.
core
On Reading Reading: Fundamental Problems of “Méta-lecture”
In his essay “Sur la Lecture,” Roland Barthes (1984) expresses his doubts regarding what he calls “Méta-lecture,” or the reading of reading. It is nothing but “un éclat d’idées, de craintes, de désirs, de jouissances, d’oppressions.” My essay ...
Elias Kreuzmair
core +1 more source

