Results 131 to 140 of about 2,117,382 (314)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Abortion and Violence in Jane Martin’s Keely and Du: Pro-Choice, Pro-Life, or Merely Provocative? [PDF]

open access: yes, 2013
Abortion and violence are global issues, yet different culture might respond to the issues somewhat differently. This study aims to reveal the abortion and violence issues in Jane Martin’s Keely and Du in terms of pro-choice and pro life movements and ...
Nurulhady, Eta Farmacelia
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The book collection of A.N. Nortsov: the history of formation, thematic coverage and significance for the creative laboratory of the owner

open access: yesНеофилология
INTRODUCTION. The book heritage of the region’s personal libraries analysis allows us to understand the reading interests’ specifics of different generations of library owners, and to clarify important aspects of the intellectual and spiritual growth of ...
R. M. Zhitin, A. G. Topilsky
doaj   +1 more source

Cultural change and reading. Heading towards a new reading culture

open access: yesEducation in the Knowledge Society, 2017
The current limitations to the reading practices can probably best be appreci- ated within the cultural changes coinciding with the step from a modern society to a post modern one. These technologies of daily life are changing the way we work, we interact and we live.
openaire   +1 more source

Bentuk Penerapan Budaya Literasi Bagi Calon Guru Sekolah Dasar Di Universitas Katolik Musi Charitas Palembang [PDF]

open access: yes, 2006
Literacy culture is associated with reading and writing skills. To foster a culture of literacy, prospective elementary school teachers need to have a culture of literacy first.
Priyanti, Maria Angelina   +1 more
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

La tertulia literaria dialógica de LIJ y la alfabetización digital [PDF]

open access: yes, 2012
The article tries to share an experience, reaching critical theory and dialogic learning, linking theory and practice in order to match learning and the formation of a critical citizenry.
Aguilar, Consol
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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