Results 41 to 50 of about 396,055 (267)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
مجلة التمكين الاجتماعيThe accelerating diffusion of generative artificial intelligence (AI) into higher education has raised concerns that the convenience of machine-produced text may be displacing sustained reading, independent reasoning and originality among undergraduates.
John Lola Okunola +1 more
doaj +1 more source
Okuma Kültürü Edinememiş Bireylere İlişkin Bir Anlatı Araştırması
Ana Dili Eğitimi Dergisi, 2021 Farklı sosyoekonomik düzeylerden gelen çocukların okuma ile ilgili yaşadıkları deneyimler nelerdir?” sorusu araştırmanın temel sorusunu oluşturmaktadır.
İbadullah Hamza Ergün, Burcu Çıldır
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The state of reading culture among secondary school students in Croatia: survey results
Knjižnica, 2018 Purpose: Reinforcement and development of reading culture of secondary school students through theoretical and research section of the paper. The concept of reading culture among students of secondary schools is connected with the path of the book ...
Andreja Zubac
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
“Best read books” in Slovenian public libraries
Knjižnica, 2008 The paper investigates hundred most borrowed books in public libraries in perspective of some trends in reading habits and general mission of public libraries.
Petra Jager
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source