Results 141 to 150 of about 102,669 (304)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Training and promotion of reading at the foundation for the training in reading – Fundalectura

open access: yes, 2023
Este documento titulado Formación y promoción de lectura en la Fundación para el Fomento de la Lectura – FUNDALECTURA, es el informe final de la pasantía realizada por la estudiante Paula Andrea Delgado en acciones de formación y promoción de lectura en ...
Delgado Cortés, Paula Andrea
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Prescripción antiprescriptiva

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Gràcia, Jordi
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Reading in the Culture of Reading : A study on the view of reading and the librarians’ reading promotion in the Literature Survey 2012

open access: yes, 2014
The purpose of this thesis is to examine the view on reading and reading promotion in the Culture of Reading (SOU 2012:65), based on three different approaches to reading and reading promotion; the pragmatic, the emancipatory and the traditionalistic ...
Kullander, Sanna
core  

Jóvenes y adolescentes hablan de lectura en la red

open access: yesOcnos, 2014
This paper documents the virtual spaces where hundreds of young people (aged 13 to 29 years old) talk daily about books, reading and authors. In these virtual spaces they exchange points of view published in their blogs, readings titles, and they ...
Gemma Lluch
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy