Results 151 to 160 of about 2,791,251 (363)
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Promotion and evacuation on standard Young tableaux of rectangle and staircase shape
(Dual-)promotion and (dual-)evacuation are bijections on SYT(\lambda) for any partition \lambda. Let c^r denote the rectangular partition (c,...,c) of height r, and let sc_k (k > 2) denote the staircase partition (k,k-1,...,1). B.
Pon, Steven, Wang, Qiang
core
Creating an online presence for a high school newspaper [PDF]
Today's journalists are expected to be fluent in much more than print media. Professional journalists are expected to provide immediate posts and frequent updates to online media, as well as full-blown stories for print publications.
Brown, Kristine C.
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Probe into the Reading Promotion of University Library in the All-Media Era
Zhen Wang
openalex +2 more sources
Reading Matters in the Academic Library: Taking the Lead from Public Librarians [PDF]
With the increasing virtualization of resources, reference service, and instruction, college students have fewer reasons to visit the academic library, a place they believe lacks relevance in their lives.
Dewan, Pauline
core +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Passioner, värden och kontradiktioner: Tre röster om läsfrämjandets hinder och möjligheter
In an ongoing research project, we examine reading promotion work in Sweden, where reading is framed as being in crisis, and where different actors offer solutions for this.
Magnus Persson, Elin Sundström Sjödin
doaj +1 more source

