Results 61 to 70 of about 802,432 (313)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The EU and Bosnia and Herzegovina: Democracy promotion within the limits of the "ethnic conflict" paradigm [PDF]
, 2011 Seeking to contribute to the emerging debate about the substance of EU democracy promotion policies, this paper takes as its focus Bosnia and Herzegovina, where the EU‟s current democracy promotion efforts are primarily focused on reform of the country‟s
Cooley, Laurence
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Läsarengagemang, bildtolkning och identifikation
Barnboken: Tidskrift för Barnlitteraturforskning, 2022 Reader Engagement, Interpretation, and Identification: Children’s Letters to the Christmas Annual Jultomten The article examines a selection of children’s letters sent to the editor of the Swedish annual Christmas publication Jultomten (Father ...
Sirkka Ivakko, Björn Sundmark
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The promotion of reading in Education Framework [PDF]
Ocnos, 2012 The research implants a theoretical-practical vision of reading promotion at the educative field. On one hand, they show us the state of the issue focusing on the legislative field, the research and promotion of virtual reading and, concretely, in the ...
Maite Monar van Vliet
doaj
, 2019 This book chapter describes the work of liaison librarians. After reading this chapter, you will be able to describe common qualifications and responsibilities of liaisons in order to determine whether liaisonship is suitable for your needs and interests
Glover, John
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Promoting reading skills in CLIL
Pulso. Revista de educación, 2016 El aprendizaje integrado de contenido y lenguas extranjeras (AICLE) ha sido ampliamente implementado en nuestras instituciones educativas a través de diferentes enfoques. AICLE puede incluir una gran variedad de recursos de enseñanza pero este nuevo marco debe implicar una perspectiva innovadora que supere las restricciones del curriculum tradicional ...
Garipova, Nailya +1 more
openaire +4 more sources