Results 131 to 140 of about 1,665,006 (312)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

We Read but How: Research on Reading and Reading Comprehension Skills

open access: yese-Kafkas Eğitim Araştırmaları Dergisi
Reading and reading comprehension skills are among the most basic language skills. Therefore, these skills should be acquired at an early age. Although there are studies in terms of reading in Türkiye, it was seen that reading comprehension skills are ...
Mehmet Arif Bozan
doaj   +1 more source

Impact of the home literacy environment on the L1 reading frequencies of Thai university students: Implications for the learning of an L2 [PDF]

open access: yes, 2007
In the Information Age, reading is a critical skill for accessing information and updating skills. However, reluctant readership in L1 may prevent many societies from fully participating in the global community. This reluctance to read may also slow the
Ferriman, Nicholas
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The relationship between reading comprehension and critical thinking among EFL learners

open access: yesLitera
Having students think critically is essential to their achieving a successful life, and thus, to develop the society they live in. Reading and critical thinking skills, are essential to acquiring knowledge, especially with foreign languages.
Alaa Salem Alshehri
doaj   +1 more source

Shared Reading Activities: A Recommendation For Deaf Children [PDF]

open access: yes, 2015
There should be a focus on fun in shared reading activities with preschoolers in order to prepare them for later literacy, particularly those at risk of a poor foundation in a first language (L1), including deaf children (here “deaf” covers hard of ...
Mirus, G., Napoli, Donna Jo
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

THE CORRELATION BETWEEN CRITICAL THINKING SKILLS AND CRITICAL READING SKILLS OF THE ENGLISH EDUCATION STUDY PROGRAM STUDENTS OF SRIWIJAYA UNIVERSITY

open access: yesEdukasi: Jurnal Pendidikan dan Pengajaran, 2016
Critical thinking skill is one of the most crucial life skills that should be possessed by the students. The objectives of this study were: (1) to find out whether or not there was a significant correlation between student’s critical thinking and ...
Rahma Dianti
doaj  

The Enhanced Reading Opportunities Study: Findings from the Second Year of Implementation [PDF]

open access: yes, 2008
According to the National Assessment of Educational Progress, a majority of ninth-graders in low-performing high schools begin their freshman year with significant reading difficulties.
Elizabeth Nelson   +4 more
core  

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