Results 191 to 200 of about 1,665,006 (312)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

The Effects of Non-Guided Versus Guided Podcast Production on Perception of English Reading Skills in Undergraduate Nursing Students: A Quasi-Experimental Study. [PDF]

Nurs Rep
Phuwayanon S, Phuwayanon S, Namprom N, Woragidpoonpol P, Daroonratsamee S, Bressington DT.   +5 more
europepmc   +1 more source

Improving Reading Skills Using a Computerized Phonological Training Program in Early Readers with Reading Difficulties. [PDF]

Int J Environ Res Public Health, 2022
Forné S, López-Sala A, Mateu-Estivill R, Adan A, Caldú X, Rifà-Ros X, Serra-Grabulosa JM.   +6 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Dyslexia Polygenic Index and Socio-Economic Status Interaction Effects on Reading Skills in Australia and the United Kingdom. [PDF]

Behav Genet
Bicona D, Mountford HS, Bridges EC, Fontanillas P, Martin NG, Fisher SE, Bates TC, Luciano M, 23andMe Research Team.   +8 more
europepmc   +1 more source

Relative heritage language and majority language use before school start explains variance in 2^nd grade majority language but not reading skills. [PDF]

Front Psychol, 2023
Højen A, Bleses D.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Do Mathematics and Reading Skills Impact Student Science Outcomes? [PDF]

J Learn Disabil
Doabler CT, Rojo M, Gersib JA, Fall AM, Longhi MA, Lovette GE, Roberts G, Uy J, Johnson K, Ghafghazi S, Phelps JB, Powell SR, Therrien WJ.   +12 more
europepmc   +1 more source

Occurrence of Reading Skills in a National Age Cohort of Norwegian Children with Down Syndrome: What Characterizes Those Who Develop Early Reading Skills? [PDF]

Brain Sci, 2021
Næss KB, Nygaard E, Smith E.
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source