Results 121 to 130 of about 1,941,882 (284)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Computer-based programs on acquisition of reading skills in schoolchildren (review of contemporary foreign investigations) [PDF]

open access: yesСовременная зарубежная психология, 2015
The article presents a description of 17 computer-based programs, which were used over the last 5 years (2008—2013) in 15 studies of computer-assisted reading instruction and intervention of schoolchildren.
Prikhoda N.A.
doaj  

Воспроизведение этнической концептуальной картины мира в украинском, русском, французском и арабском переводах сказки О.Уальда "Соловей и роза" [PDF]

open access: yes, 2015
Reading is central to Cognitive Poetics (Stockwell 2002: 1), yet, what about the reading of a translator? Schulte claims: "The translator develops reading techniques that are distinctly different from those of a critic or scholar".
Боучуачі, Суфьян   +1 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Comparing Reading Aloud and Silent Reading Strategies in Enhancing Reading Comprehension Among Elementary Students

open access: yesBidayatuna
The purpose of this study was to compare the effectiveness of using reading aloud and sustained silent reading strategies on the ability to explain reading content in terms of the opinions/perceptions of high-grade students.
M. Habibie, Lasti Rahma Winta
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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