Results 121 to 130 of about 1,940,419 (280)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Воспроизведение этнической концептуальной картины мира в украинском, русском, французском и арабском переводах сказки О.Уальда "Соловей и роза" [PDF]

, 2015
Reading is central to Cognitive Poetics (Stockwell 2002: 1), yet, what about the reading of a translator? Schulte claims: "The translator develops reading techniques that are distinctly different from those of a critic or scholar".
Боучуачі, Суфьян, Шурма, Світлана   +1 more
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Name-passing calculi and crypto-primitives: A survey

, 2004
The paper surveys the literature on high-level name-passing process calculi, and their extensions with cryptographic primitives. The survey is by no means exhaustive, for essentially two reasons.
Bugliesi, M., Castagna, G., Crafa, S., Focardi, R., Sassone, V.   +4 more
core  

Taxonomy Of Language Teaching Techniques In Teaching Reading [PDF]

, 2014
English language teaching techniques have various categorization.Those techniques covering for main skills in English namely reading,listening, speaking and writing. The concept incorporatesclassification of type of activity that enables teachers to pick
Humaera, I. (Isna)
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Carbon Nanotube Emissions from Arc Discharge Production: Classification of Particle Types with Electron Microscopy and Comparison with Direct Reading Techniques. [PDF]

Ann Occup Hyg, 2016
Ludvigsson L, Isaxon C, Nilsson PT, Tinnerberg H, Messing ME, Rissler J, Skaug V, Gudmundsson A, Bohgard M, Hedmer M, Pagels J.   +10 more
europepmc   +1 more source

Literary reading: interactive methods and techniques [PDF]

Формування читацької компетентності молодших школярів, яка є індивідуальним інтегрованим утворенням, передбачає різні види завдань на перечитування, розуміння, відтворення і зміни текстів, залежно від мети опрацювання, їх жанру, обсягу, складності.
Савченко, Олександра Яківна
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source