A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
The Sustainable Development Goals Report 2024, published by the United Nations, highlights quality education as a priority goal, emphasising its essential role in facilitating the achievement of other goals.
Inga Linde, Linda Daniela
doaj +1 more source
Head Tracking via Robust Registration in Texture Map Images [PDF]
A novel method for 3D head tracking in the presence of large head rotations and facial expression changes is described. Tracking is formulated in terms of color image registration in the texture map of a 3D surface model.
Isidoro, John +2 more
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Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
The internet milieu: individualization within a globalised community [PDF]
Communication technologies have become deeply embedded in our lives, mediating the ways in which information is presented. Due to the global nature of this channel of communication, the world has shrunk and members of the internet may share similar ...
Lee, Siew Chin, Lin, Luck Kee
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Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
A study to determine the effect of music and proof-reading techniques on creative writing in grades five and six [PDF]
Thesis (Ed.M.)--Boston ...
Manahan, Ardena Miller
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Carbon Nanotube Emissions from Arc Discharge Production: Classification of Particle Types with Electron Microscopy and Comparison with Direct Reading Techniques. [PDF]
Ludvigsson L +10 more
europepmc +1 more source
Radio frequency identification (RFID) technologies for locating warehouse resources: A conceptual framework [PDF]
Copyright @ 2012 Information Technology SocietyIn the supply chain, a warehouse is a crucial component for linking all chain parties. It is necessary to track the real time resource location and status to support warehouse operations effectively ...
Aktas, E, Ali, M, Hassan, M
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