Results 11 to 20 of about 9,132 (172)

Teaching French Literature in a Foreign Language

open access: yesJournal of Modern Languages, 2017
This study considers the methods of teaching French literature applicable in other languages. It also compares the relation between researchers who are striving for the more abstract and power models and those who are interested in the intersubjective ...
Marie Laure Poletti
doaj   +14 more sources

Variations rythmiques sur un récit pour la jeunesse de Virginia Woolf : sur cinq albums illustrés de Nurse Lugton…

open access: yesStrenae, 2016
Between 1966 and 2013, five picture books were published in English, Italian and French, posthumous variations on a fable that Virginia Woolf probably wrote for one of her nieces.
Caroline Marie
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Stéréotypie et transferts culturels : d’une Bovary l’autre (Minelli, Oliveira, Fontaine, Barthes)

open access: yesCarnets
Based on the study of some adaptations of Gustave Flaubert's Madame Bovary (Minelli, Oliveira, Fontaine, Barthes), this contribution will consider the question of cultural appropriation and transfer involved in filmic rewriting. In the triple distance of
Florence Pellegrini
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Wesh ou ouèche ? Les trucages orthographiques comme contrat de lecture dans la série d’albums Les Cahiers d’Esther de Riad Sattouf

open access: yesComicalités
This article combines a sociolinguistic and literary approach to examine representations of spoken French in a corpus of graphic literature. It analyzes the orthographic variations of wesh/ouèche in Les Cahiers d’Esther by Riad Sattouf, exploring their ...
Emmanuelle Guerin, Donatienne Woerly
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

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