Results 131 to 140 of about 63,887 (261)

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Perfect diagnostic agreement between canine- and feline-specific parvovirus PoC antigen kits in feline panleukopenia. [PDF]

Vet Q
Safwat MS, Farouk MM, Zaki Anwer A, Ali ME, Shahen NM, Abdelwahed DA, Hassanien RT, Afify AF, Ali MH, Eid S, Mansour ONO, Sargious MAN, Abdallah MI, Karam R, El-Sayed M S.   +14 more
europepmc   +1 more source

[Liquid-phase electrophoresis in the analysis of antigen-antibody interactions in erythrocyte diagnostic reagent kits].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1983
A Iu, Ivanov, A I, Miroshnikov
openaire   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Can prothrombin time assays withstand the influence of antiprothrombin and anti-β2-glycoprotein I antibodies on the international normalized ratio? [PDF]

Res Pract Thromb Haemost
Vandevelde A, Devreese KMJ.
europepmc   +1 more source

GloPID-R report on Chikungunya, O\u27nyong-nyong and Mayaro virus, part I: Biological diagnostics [PDF]

, 2019
Diamond, Michael S, et al,
core   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Comprehensive Review on Viral RNA Extraction Strategies for Enhanced Molecular Diagnostics. [PDF]

Interdiscip Perspect Infect Dis
Made Artika I, Ma'roef CN, Johar E, Yudhaputri FA, Myint KSA.   +4 more
europepmc   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Isolation and characterization of peroxidase from potato leaves Solanum tuberosum: Application in glucose diagnostic kit. [PDF]

J Genet Eng Biotechnol
Masoud HMM, Abdel-Monsef MM, Helmy MS, Esa SS, Darwish DA.   +4 more
europepmc   +1 more source