Results 131 to 140 of about 1,703,411 (334)
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Sensitivity and specificity of three commercial NS1 and IgM/IgG rapid diagnostic test kits.
, 2019 Sensitivity and specificity of three commercial NS1 and IgM/IgG rapid diagnostic test kits.
Chae Seung Lim (1888042) +5 more
core +1 more source
Advanced Science, EarlyView.Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Description of the diagnostic kits for human visceral leishmaniasis included in the study.
, 2019 Description of the diagnostic kits for human visceral leishmaniasis included in the study.
Edward Oliveira (112010) +7 more
core +1 more source
Advanced Science, EarlyView.An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang +14 more
wiley +1 more source
Advanced Science, EarlyView.Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
Sensitivities of anti-HCV rapid diagnostic test kits by HIV sero-status.
, 2019 Sensitivities of anti-HCV rapid diagnostic test kits by HIV sero-status.
Kartik Kacholia (6239897) +10 more
core +1 more source
Evaluation of polyclonal antibodies raised in rabbits against dengue NS1 antigen
Scientific ReportsDengue, a vector-borne disease caused by the dengue virus (DENV), is spread by Aedes mosquitoes like, Aedes aegypti and Aedes albopictus. In the absence of antiviral drugs or vaccines, dengue prevention is centered on mosquito vector control.
Philip Raj Abraham +8 more
doaj +1 more source
Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source