Results 111 to 120 of about 33,061 (260)

RGS14 (414)-mediated prevention of an episodic memory loss: a study of molecular mechanism [PDF]

, 2015
A large proportion of human populations suffer memory impairments either caused by normal aging or afflicted by diverse neurological and neurodegenerative diseases. Memory enhancers and other drugs tested so far against memory loss have failed to produce
Navarro Lobato, Irene
core   +1 more source

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

Advanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin, Jose Crugeiras, Chiara Bisquoli, Davide Barboni, Martina Catani, Bruno Rodríguez‐Meana, Rita Boaretto, Michele Albicini, Stefano Caramori, Claudio Trapella, Thomas Stieglitz, Yara Baslan, Hanna Karlsson‐Fernberg, Fernanda L. Narvaez‐Chicaiza, Edoardo Marchini, Alberto Cavazzini, Ruben López‐Vales, Maria Asplund, Xavier Navarro, Stefano Carli   +19 more
wiley   +1 more source

Assessment of the physical and chemical properties of vaginal discharge for the diagnosis of endometritis in dairy cattle [PDF]

Veterinary World
Background and Aim: Postpartum endometritis is a major cause of infertility in dairy cattle, impacting herd productivity and economic sustainability.
Nest Dale Bartolome, Ruchikon Jongsuwanwattana, Sariya Asawakarn, Siriwat Suadsong, Kiattisak Sangpradit, Theerawat Swangchan-Uthai   +5 more
doaj   +1 more source

Impact of Fiber Orientation in Electrospun PLA Scaffolds on Fluid Dynamics in a Custom Microfluidic Device

Advanced Healthcare Materials, EarlyView.
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana, Maria Testa, Chiara Di Marco, Francesco Lopresti, Vincenzo La Carrubba   +4 more
wiley   +1 more source

All that is blood is not schistosomiasis: experiences with reagent strip testing for urogenital schistosomiasis with special consideration to very-low prevalence settings

Parasites & Vectors, 2015
Background Reagent strip testing for microhaematuria has long been used for community diagnosis of Schistosoma haematobium. Sensitivities and specificities are reasonable, and hence, microhaematuria can serve as a proxy for S.
Stefanie J. Krauth, Helena Greter, Katarina Stete, Jean T. Coulibaly, Seïdinan I. Traoré, Bongo N. R. Ngandolo, Louise Y. Achi, Jakob Zinsstag, Eliézer K. N’Goran, Jürg Utzinger   +9 more
doaj   +1 more source

EVALUATION OF LEUKOCYTE ESTERASE REAGENT STRIPS TEST IN THE DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS IN CHILDREN WITH CIRRHOSIS

Arquivos de Gastroenterologia, 2015
BackgroundSpontaneous bacterial peritonitis is defined as an ascetic fluid infection without an evident intra-abdominal surgically treatable source.
Naser HONAR, Bita GERAMIZADEH, Seyed-Mohsen DEHGHANI, Gholamreza KALVANDI, Iraj SHAHRAMIAN, Asghar RAHMANI, Hazhir JAVAHERIZADEH   +6 more
doaj   +1 more source

Screen-printed platinum electrodes for the detection of cupric and ferric ions in high chloride backgrounds

, 2010
Screen-printed platinum electrodes developed for use in corrosion monitoring applications have been used to detect cupric and ferric ions both individually and as mixtures in a background of 3.5% by weight sodium chloride and in the presence of dissolved
Cranny, Andrew, Harris, Nick, Lewis, Adam, Nie, Menyang, Stokes, Keith, Wharton, Julian, Wood, Robert   +6 more
core  

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Evaluation of two eco-friendly neutralizers for a spectrum of tissue fixatives for biomedical applications. [PDF]

, 2018
Formaldehyde is a widely used aldehyde in biomedical applications, including tissue fixation. It is this same fixative property that can result in toxicity if aldehydes are improperly discarded.
Carmichael, Stanley Thomas, Prakash, Roshini   +1 more
core