Results 211 to 220 of about 219,284 (275)

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

Comparison of laboratory-developed methods for aztreonam plus ceftazidime-avibactam antimicrobial susceptibility testing for metallo-beta-lactamase-producing Enterobacterales. [PDF]

J Clin Microbiol
Bhatnagar AS, Harris H, Jacobs E, Bumpus-White P, Balbuena R, Stambaugh H, Crayton K, Haynie J, Quintero Ilutsik J, Longo C, Bergman Y, Singh S, Murray M, Sabour S, Robinson ML, Machado M-J, Simner PJ.   +16 more
europepmc   +1 more source

Ultrasound‐Activated Ce(IV)‐Integrated Biomimetic Nanoplatform for Oxygenation‐Reinforced Gas‐Sonodynamic Ferroptosis and cGAS–STING‐Driven Antitumor Immunity

Advanced Science, EarlyView.
A Ce(IV)‐integrated biomimetic nanoplatform coordinates tumor oxygenation, ultrasound‐triggered carbon monoxide release, sonodynamic therapy, ferroptosis amplification, and cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) immune activation.
Mengli Ma, Yingying Wu, Yunjie Wang, Yang Li, Yijia Zhang, Zhibo Zhang, Jinzhi Peng, Xiangyu Wu, Yi Luo, Weijing Zhang, Xin Ye, Weisong Lai, Shengyu Wang, Dan Du, Wengang Li, Nan Zheng, Fanghong Luo, Ting Wu   +17 more
wiley   +1 more source

Development of a multiplex detection system for toxic <i>Amanita</i> species based on isothermal recombinase polymerase amplification and CRISPR/Cas12b technology. [PDF]

Front Mol Biosci
Li H, Ying X, Luo Z, Lu C, Zhang P.
europepmc   +1 more source

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

Au@Ag@Pt Trimetallic Nanoparticle-Enhanced Dual-Mode Lateral Flow Immunochromatographic Assay for Ultrasensitive and Rapid Detection of Acetamiprid in Plant-Based Foods. [PDF]

Foods
Li Q, Zhang X, Chen S, Guo B, Cao Q, Feng X, Yu X, Jia X, Zhang B, Wang H.   +9 more
europepmc   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

Advanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen, Yu Tang, Chengpeng Hu, Xiaoyan Duan, LingXia Min, Boya Cong, Chao Ma, Mingliang Tan, Ya Luo, Pengfei Wei, Minpeng Xu, Zhou Feng, Jingming Hou   +12 more
wiley   +1 more source

Development and validation of a rapid triple-target gold nanoparticle lateral flow immunoassay for detection of three avian mycoplasmas immunochromatographic strip test for avian mycoplasma detection. [PDF]

BMC Microbiol
Zidi S, Yacoub E, Chniba I, Chaari S, Almawi W, Ben Abdelmoumen Mardassi B.   +5 more
europepmc   +1 more source

Vacuum Heat Treatment Regulates the Bamboo-Epoxy Interface: Balancing Mechanical Performance and Thermal Stability. [PDF]

Polymers (Basel)
Liang Z, Jiang H, Tan Y.
europepmc   +1 more source

A Portable UV-LED Dual-Nafion Microfluidic Platform for Label-Free Trace Protein Preconcentration and Absorbance Detection. [PDF]

Biosensors (Basel)
Shih YJ, Chen YS, Jen CP.
europepmc   +1 more source