Results 41 to 50 of about 65,650 (304)
Post-processing treatment of conductive polymers to enhance electrical conductivity [PDF]
, 2012 A method for enhancing electrical conductivity of a film which includes at least one conductive polymer. The method includes providing the film comprising the at least one conductive polymer and at least one polymer acid, agitating the film in at least ...
Lee, Kwang Seok +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Water-soaked porous evidence:a comparison of processing methods [PDF]
, 2013 This study compared the U.K. Home Office formulation for physical developer (PD) against Oil Red O (ORO) and a modified formulation of physical developer (MPD) that uses Tween 20 instead of Synperonic-N for enhancing fingermarks.
Deacon, Paul +2 more
core +1 more source
Effect of floor type on the performance, physiological and behavioural responses of finishing beef steers [PDF]
, 2015 peer-reviewedBackground:The study objective was to investigate the effect of bare concrete slats (Control), two types of mats [(Easyfix mats (mat 1) and Irish Custom Extruder mats (mat 2)] fitted on top of concrete slats, and wood-chip to simulate deep ...
A O’Loughlin +56 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Evaluation of the RT-LAMP/CRISPR-Cas12 diagnostic method for SARS-COV-2
Acta Scientiarum. Health Sciences, 2023 Brazil is one of the countries that least performs detection tests for SARS-COV-2, even though diagnosing cases is the most effective way to control epidemics, which is crucial to guide public policies.
Graziela Parente Peduti +1 more
doaj +1 more source
Band-collision gel electrophoresis. [PDF]
, 2019 Electrophoretic mobility shift assays are widely used in gel electrophoresis to study binding interactions between different molecular species loaded into the same well.
Bikos, Dimitri A, Mason, Thomas G
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Audit in practice : surveillance for hypoglycaemia in the neonatal paediatric intensive care unit [PDF]
, 1998 Hypoglycaemia in neonates is defined as a blood glucose ≤ 2.6 mmol/1. Certain categories of babies are at particularly high risk of developing hypoglycaemia in the first few days of life, and are routinely monitored in the Neonatal Paediatric Intensive ...
Grech, Victor E., Soler, Paul
core