Results 61 to 70 of about 2,909,057 (354)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Edge-Computing Video Analytics for Real-Time Traffic Monitoring in a Smart City

Italian National Conference on Sensors, 2019
The increasing development of urban centers brings serious challenges for traffic management. In this paper, we introduce a smart visual sensor, developed for a pilot project taking place in the Australian city of Liverpool (NSW).
J. Barthélemy, Nicolas Verstaevel, H. Forehead, P. Perez   +3 more
semanticscholar   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Method for Computing Dense Optical Flow on FPGA in Real Time

Современные информационные технологии и IT-образование, 2019
One of the most actual problems in the technical vision systems is the problem of objects detection and selection in the field of the image sensor view.
Alexander V. Bratulin, Mikhail B. Nikiforov, Pavel V. Belyakov, Yevgeny Y. Kholopov   +3 more
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

A Distributed Computing Real-Time Safety System of Collaborative Robot

Elektronika ir Elektrotechnika, 2020
Robotization has become common in modern factories due to its efficiency and cost-effectiveness. Lots of robots and manipulators share their workspaces with humans what could lead to hazardous situations causing health damage or even death.
Dawid Gradolewski, Dawid Maslowski, Damian Dziak, Bartosz Jachimczyk, Siva Teja Mundlamuri, Chandran G. Prakash, Wlodek J. Kulesza   +6 more
doaj   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas   +2 more
wiley   +1 more source

On real-time and non real-time distributed computing

, 1995
In this paper, taking an algorithmic viewpoint, we explore the differences existing between the class of non real-time computing problems (ℵℜ) versus the class of real-time computing problems (ℜ). We show how a problem in class ℜ can be transformed into its counterpart in class ℵℜ. Claims of real-time behavior made for solutions to problems in class ℵℜ
openaire   +2 more sources

Dimensioning the MAORY real time computer

SPIE Proceedings, 2016
The MAORY system is the Multi-Adaptive Optics module for the European Extremely Large Telescope first light. MAORY should provide high and homogeneous image quality over the MICADO Field of View (about 1 arcmin diameter) and still an acceptable correction up to the 3 arcmin technical Field of View.
SCHREIBER, LAURA, DIOLAITI, EMILIANO, Arcidiacono, Carmelo, Baruffolo, Andrea, BREGOLI, GIOVANNI, Cascone, Enrico, COSENTINO, GIUSEPPE, ESPOSITO, SIMONE, Felini, Corrado, FOPPIANI, ITALO, Ciliegi, Paolo, Feautrier, Philippe, TORRONI, PAOLO   +12 more
openaire   +4 more sources