Results 61 to 70 of about 244,199 (317)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

An Architecture-Based Adaptation Framework for Soft Real-Time Applications

open access: yesDianxin kexue, 2012
Driven by the proliferation of mobile and pervasive computing, real-time systems are increasingly used in dynamic changing environments with variable user needs, hosting real-time applications ranging in number and nature over time.
Xiaoan Bao   +3 more
doaj   +2 more sources

Efficient and explainable MRI brain tumor classification via Adaptive GAN-based data augmentation

open access: yesArray
Accurate brain tumor diagnosis from MRI is critical, but state-of-the-art deep learning (DL) models are computationally expensive and require large datasets, limiting clinical deployment.
Anbazhagan Mahadevan   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Towards Emotionally Aware AI Smart Classroom: Current Issues and Directions for Engineering and Education

open access: yesIEEE Access, 2018
Future smart classrooms that we envision will significantly enhance learning experience and seamless communication among students and teachers using real-time sensing and machine intelligence.
Yelin Kim   +2 more
doaj   +1 more source

Real-Time Methods in Reversible Computation

open access: yes, 2015
Bennett has shown how to simulate arbitrary forwards-only computations by fully reversible computation. In particular he has given a space-efficient linear time simulation. After describing a different linear-time reversible simulation with improved space efficiency, we initiate the study of real-time simulations.
Pesu, T, Phillips, ICC
openaire   +2 more sources

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