Results 61 to 70 of about 238,739 (317)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A Real-Time Object Detection Processor With xnor-Based Variable-Precision Computing Unit [PDF]
, 2023 Wonjae Lee +4 more
openalex +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Reinventing Computing for Real Time [PDF]
, 2007 This paper studies models of computation, software techniques, and analytical models for distributed timed systems. By "timed systems" we mean those where timeliness is an essential part of the behavior. By "distributed systems" we mean computational systems that are interconnected on a network.
Edward A. Lee, Yang Zhao
openaire +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
An Architecture-Based Adaptation Framework for Soft Real-Time Applications
Dianxin kexue, 2012 Driven by the proliferation of mobile and pervasive computing, real-time systems are increasingly used in dynamic changing environments with variable user needs, hosting real-time applications ranging in number and nature over time.
Xiaoan Bao +3 more
doaj +2 more sources
Efficient and explainable MRI brain tumor classification via Adaptive GAN-based data augmentation
ArrayAccurate brain tumor diagnosis from MRI is critical, but state-of-the-art deep learning (DL) models are computationally expensive and require large datasets, limiting clinical deployment.
Anbazhagan Mahadevan +5 more
doaj +1 more source
On real-time and non real-time distributed computing
, 1995 In this paper, taking an algorithmic viewpoint, we explore the differences existing between the class of non real-time computing problems (ℵℜ) versus the class of real-time computing problems (ℜ). We show how a problem in class ℜ can be transformed into its counterpart in class ℵℜ. Claims of real-time behavior made for solutions to problems in class ℵℜ
openaire +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source