Results 71 to 80 of about 21,652,291 (267)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Geodesy and Geodynamics, 2020 This article focuses on the performance analysis of both real-time and post-mission kinematic precise point positioning (PPP) in challenging marine environments.
Serdar Erol +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Real-Time Orbit Determination of Korean Navigation Satellite System based on Multi-GNSS Precise Point Positioning [PDF]
E3S Web of Conferences, 2019 This study proposes real-time orbit/clock determination of Korean Navigation Satellite System (KNSS), which employs the kinematic precise point positioning (PPP) solutions of multiple Global Navigation Satellite System (multi-GNSS) to compensate for ...
Kim Gimin +3 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Evaluation of Real-Time PPP-Based Tide Measurement Using IGS Real-Time Service
Sensors, 2020 Tide data plays a key role in many marine scientific research fields such as seafloor topography measurement and navigation safety. To obtain reliable tide data, various methods have been proposed, e.g., tide station measurement, satellite altimeter ...
Mingwei Di +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Real-Time GPS/Galileo Precise Point Positioning Using NAVCAST Real-Time Corrections
Positioning, 2019 Real-time precise point positioning (PPP) is possible through the use of real-time precise satellite orbit and clock corrections, which are available through a number of organizations including the International GNSS Service (IGS) real-time service (IGS-RTS). Unfortunately, IGS-RTS is only available for the GPS and GLONASS constellations.
Abdelsatar Elmezayen, Ahmed El-Rabbany
openaire +2 more sources
Assessment of Different Real Time Precise Point Positioning Correction Over the Sea Area [PDF]
, 2019 In a global scale, the accuracy of Real Time Precise Point Positioning (RT-PPP) method in Global Navigation Satellite System (GNSS) point positioning is within cm to dm level.
Gumilar, I. (Irwan) +9 more
core +1 more source