Results 81 to 90 of about 98,892 (314)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A Packet Scheduling Algorithm for Real-time Traffics in OFDMA Systems
工程科学与技术, 2009 :In mobile communication systems, users in good channel state were allocated excessive resources by most of scheduling algorithms when dealing with real-time traffics, while users in bad channel state got relatively few scheduling chances.
Zheng Pei-Chao +3 more
doaj
Research and design of hybrid scheduling system of node operating system for cyber physical systems
Tongxin xuebao, 2013 In accordance with the new characteristics of physical,internet and intelligence of CPS,a hybrid scheduling system was designed for CPS node operating system with real-time performance,flexibility,and adaptability.Based on the in-depth study of the ...
Xiao-zhou DU +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Task Scheduling Model for Multi-CPU and Multi-Hard Disk Drive in Soft Real-time Systems [PDF]
, 2019 Zeynab Mohseni +2 more
openalex +1 more source
An Architecture for Real-Time Distributed Scheduling.
AI Mag., 1992 Industrial managers, engineers, and technologists have many expectations from artificial intelligence and its application to knowledge-based systems. Although the past decade has witnessed a number of innovative applications of AI in manufacturing, the field is still in its infancy and holds even greater promise for the future.
Hadavi, Khosrow +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Using Deep Reinforcement Learning for mmWave Real-Time Scheduling [PDF]
, 2022 Barak Gahtan +3 more
openalex +1 more source