Results 41 to 50 of about 20,202,611 (293)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Dynamic scheduling of parallel real-time jobs by modelling spare capabilities in heterogeneous clusters [PDF]

, 2003
In this research, a scenario is assumed where periodic real-time jobs are being run on a heterogeneous cluster of computers, and new aperiodic parallel real-time jobs' modelled by Directed Acyclic Graphs (DAG), arrive at the system dynamically.
Nudd, G. R., Stephen A. Jarvis, Nudd, Graham R., Jarvis, Stephen A.; id_orcid, He, Ligang, Daniel P. Spooner, Spooner, Daniel P., Ligang He, Jarvis, Stephen A., Graham R. Nudd   +9 more
core   +1 more source

Simulation of Real-Time Systems

Transport and Telecommunication
This article presents the development of a real-time system simulator and discusses the results obtained through its application. The simulator is designed in accordance with the fundamental principles of real-time systems, incorporating traffic sources ...
Hanczewski Sławomir, Weissenberg Joanna
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Real-time Sponge and Fluid Simulation

, 2022
In this paper we present an approach to couple PBD simulation of deformable porous objects with SPH. We propose solutions for simulating the absorption and discharge of fluid by the sponge, and the effect of the fluid on sponge behaviour. We maintain the
Burkus, Viktória, Kárpáti, Attila, Szécsi, László, Klár, Gergely   +3 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Asynchronous multi‐rate method of real‐time simulation for active distribution networks

IET Renewable Power Generation, 2023
The real‐time simulation of active distribution networks (ADNs) can provide an accurate insight into transient behaviours, but faces challenges in simulation efficiency and flexibility brought by larger system scales and wider time‐scale ranges.
Hao Fu, Peng Li, Xiaopeng Fu, Zhiying Wang, Jinyue Yan, Jianzhong Wu, Chengshan Wang   +6 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

A Real-time Service Oriented Infrastructure [PDF]

, 2010
The advancements in distributed computing have driven the emergence of service-based infrastructures that allow for on-demand provision of ICT assets. Taking into consideration the complexity of distributed environments, significant challenges exist in ...
Michael Boniface, Voith, T, Soren Berger, Cucinotta, T, Tommaso Cucinott, Dimosthenis Kyriazis, Voith, Thomas, Eduardo Oliveros, Oberle, K, Andreas Menychtas, Karsten Oberle, Kyriazis, D, Kyriazis, Dimosthenis, Menychtas, Andreas, Oliveros, Eduardo, Thomas Voith, Oberle, Karsten, Menychtas, A, Tommaso Cucinotta, Berger, Sören, George Kousiouris, Oliveros, E, Kousiouris, George, Berger, S, Boniface, Mike, Kousiouris, G, Cucinotta, Tommaso   +26 more
core   +1 more source