Results 151 to 160 of about 23,126,500 (355)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Little Data Book 2009

, 2009
The little data book 2009 is a pocket edition of World Development Indicators (WDI) 2009. It is intended as a quick reference for users of the WDI 2009 book and CD-ROM and WDI online, and electronic subscription
World Bank
core   +1 more source

Demographics and Clinical Characteristics among Patients with Distinct Psychosocial Burden Profiles Related to Vitiligo: Results of a Latent Class Analysis

Dermatology and Therapy
Introduction Vitiligo may negatively impact quality of life (QOL). This study aimed to classify patients on the basis of the impact of vitiligo on emotional/psychological and social functioning and describe patient characteristics and patient-reported ...
Kent A. Hanson, Khaled Ezzedine, Jenny Austin, Peter Anderson, Simran Marwaha, Samantha K. Kurosky, Roni Adiri, James Piercy, Ernest H. Law   +8 more
doaj   +1 more source

Agreement between people with obesity and their treating physicians on behavioral and psychological phenotypes in real-world obesity care

Obesity Pillars
Background: Awareness is growing that body mass index (BMI) alone does not capture the behavioral, psychological and physiological heterogeneity of obesity.
David M. Savastano, Pamela Appel, Andrea Leith, Giorgio Castellano, Lewis Harrison, Victoria Higgins   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Little Green Data Book 2017

, 2017
The Little Green Data Book 2017 is based on World Development Indicators 2017 and its online database. Defining, gathering, and disseminating international statistics is a collective effort of many people and organizations.
World Bank
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Memorias de la Real Academia de Ciencias de Madrid

Na portada: 3ª Serie. Ciencias naturales. Tomo III. 1ª ParteAntepEsc. real xil.
Real Academia de Ciencias de Madrid
core  

Patient Burden of Nonsegmental Vitiligo: A US Real-World Survey of Dermatologists and Their Patients

Dermatology and Therapy
Introduction Vitiligo is a chronic autoimmune disease characterized by destruction of melanocytes, leading to skin depigmentation. Vitiligo can have a high quality-of-life burden and profound impact on psychosocial well-being.
David Rosmarin, Jennifer H. Lofland, Simran Marwaha, James Piercy, Peter Anderson, Jinan Liu   +5 more
doaj   +1 more source

Psychiatry in the real world

Frontiers in Psychiatry
Although diagnostic and therapeutic issues are relatively settled in formal psychiatry, there is considerable confusion among the public. In the real world, there is notable misunderstanding of terminology and concepts, not only of diagnoses and treatments, but also of the titles and characteristics of mental health professionals and institutions ...
openaire   +3 more sources