Results 141 to 150 of about 2,274,708 (332)

Caracterización y análisis de modelos de evaluación económica de proyectos de inversión bajo incertidumbre

open access: yesIngenieria Industrial, 2009
Este articulo presenta los métodos  actualmente disponibles para la evaluación de proyectos, dejando de manifiesto las falencias de los métodos tradicionales como el Método de Flujos de Caja Descontados, cuando son usados para evaluar proyectos con alta ...
Feliciano Alejandro Garcia Ruiz   +1 more
doaj  

Real Options Analysis and Strategic Decision Making [PDF]

open access: green, 2001
Edward H. Bowman, Gary T. Moskowitz
openalex   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

THE LIMITATIONS OF NO-ARBITRAGE ARGUMENTS FOR REAL OPTIONS [PDF]

open access: green, 2001
Friedrich Hubalek, Walter Schachermayer
openalex   +1 more source

On Real Options and Information Costs. [PDF]

open access: yes
This paper presents a simple framework for the use of traditional capital budgeting models and the valuation of several real options in the presence of shadow costs of incomplete information. Information costs can be viewed as sunk costs in the spirit of
Bellalah, Mondher, El Farissi, Inass
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Pricing Reliability Options under different electricity prices' regimes [PDF]

open access: yesarXiv, 2019
Reliability Options are capacity remuneration mechanisms aimed at enhancing security of supply in electricity systems. They can be framed as call options on electricity sold by power producers to System Operators. This paper provides a comprehensive mathematical treatment of Reliability Options.
arxiv  

Real options and scenario planning as a way to gain insight into flexibility in health care real estate management, a first exploration [PDF]

open access: yes, 2010
Real estate management in health care faces many uncertainties, and more specific in the Netherlands even more because of changing regulations regarding\ud the financing of capital costs.
Blanken, A.   +2 more
core   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy