Corporate social responsibility: a real options approach to the challenge of financial sustainability. [PDF]
PLoS One, 2015 Bosch-Badia MT +2 more
europepmc +1 more source
Investment Decision in a Broadband Internet Network: A Real Options Approach [PDF]
This article is a case study analysing the decision of a telecommunications operator to roll out ADSL infrastructures in areas of low population density.
Charlotte KRYCHOWSKI
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
What a Difference a Stochastic Process Makes: Epidemiological-Based Real Options Models of Optimal Treatment of Disease. [PDF]
Environ Resour Econ (Dordr), 2018 Dangerfield CE +3 more
europepmc +1 more source
Valuing Voluntary Disclosure using a Real Options Approach [PDF]
This paper outlines a real options approach to valuing those announcements which are made by firms outside their legal requirements. From the firm's perspective, information is disclosed only if the manager of the firm is sufficiently certain that the ...
Jacco J.J. Thijssen, Laura Delaney
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Mixed contracts for the newsvendor problem with real options [PDF]
In this paper we consider the newsvendor model with real options. We consider a mixed contract where the retailer can order a combination of q units subject to the conditions in a classical newsvendor contract and Q real options on the same items.
Jörnsten, Kurt +3 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Real options for adaptive decisions in primary industries [PDF]
The long term sustainability of Australian crop and livestock farms is threatened with climate change and climate variability. In response, farmers may decide to (1) adjust practices and technologies, (2) change production systems, or (3) transform their
Greg Hertzler, Tim Capon, Todd Sanderson
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source