Results 81 to 90 of about 552,390 (336)
Explaining refugee flows. Understanding the 2015 European refugee crisis through a real options lens. [PDF]
Peters L, Engelen PJ, Cassimon D.
europepmc +1 more source
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang+6 more
wiley +1 more source
Company Value, Real Options and Financial Leverage
This paper deals with determining of the value of companies and financial leverage. The author tries to find the optimum debt ratio for selected companies in the Czech Republic. The method of yield option extension is used for evaluating a company.
O. Drahovzal
doaj
Valuing Indoor Air Quality Benefits in a Healthcare Construction Project with Real Option Analysis
Indoor air quality (IAQ) can produce significant economic benefits for the tenant during the use of the building. However, currently the potential economic benefits on a tenant’s employees’ health and performance are not considered in feasibility studies
Juho-Kusti Kajander+2 more
doaj +1 more source
The optimal performance target of valuation adjustment mechanism agreement with real options perspective. [PDF]
Xue Y, Yun X.
europepmc +1 more source
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam+2 more
wiley +1 more source
Kalman filter approach to real options with active learning. [PDF]
Sund S, Sendstad LH, Thijssen JJJ.
europepmc +1 more source
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto+3 more
wiley +1 more source
Abstract The past two decades have produced extensive evidence on the manifold and severe outcomes for victims of aggression exposure in the workplace. However, due to the dominating individual‐centered approach, most findings miss a social network perspective.
Alexander Herrmann+2 more
wiley +1 more source