Results 81 to 90 of about 2,631,234 (303)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Real Option Applications to Information Security [PDF]

open access: yes
Real options present advantages over the standard discounting methods. In this paper we analyze them briefly and examine their potential applications on information security.
Pythagoras PETRATOS
core  

Valuing Indoor Air Quality Benefits in a Healthcare Construction Project with Real Option Analysis

open access: yesBuildings, 2014
Indoor air quality (IAQ) can produce significant economic benefits for the tenant during the use of the building. However, currently the potential economic benefits on a tenant’s employees’ health and performance are not considered in feasibility studies
Juho-Kusti Kajander   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Real Options Theory for Law Maker. [PDF]

open access: yes
In rapidly changing areas of law, the writing of rules is a challenging issue for lawmakers. Obsolescence impede law to capture the objective of an underlying policy. The legislator, the judge and the regulator are considered as producers of law who have
Bruno Deffains, Marie Obidzinski
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Valuation of a Company Producing and Trading Seaweed for Human Consumption: Classical Methods vs. Real Options. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Pérez-Vas R   +2 more
europepmc   +1 more source

Real options and scenario planning as a way to gain insight into flexibility in health care real estate management, a first exploration [PDF]

open access: yes, 2010
Real estate management in health care faces many uncertainties, and more specific in the Netherlands even more because of changing regulations regarding\ud the financing of capital costs.
Blanken, A.   +2 more
core   +2 more sources

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