Results 141 to 150 of about 3,428,091 (391)

A Real Options Analysis of Automatic Milking Systems [PDF]

Automatic, or robotic, milking systems have the potential to significantly change the way milk is produced on U.S. dairy farms. However, there is a high degree of uncertainty associated with adoption of this new technology.
Engel, Phoebe D., Hyde, Jeffrey
core   +1 more source

Building Real Options into Physical Systems with Stochastic Mixed-Integer Programming [PDF]

, 2005
The problem of building real options into physical systems has three features: real options are not as easily defined as financial options; path-dependency and interdependencies among projects mean that the standard tools of options analysis tools are ...
de Neufville, Richard, Wang, Tao
core  

Investment in Wind Power and Pumped Storage in a Real Options Model - A Policy Analysis [PDF]

, 2011
Wolf-Heinrich Reuter, Sabine Fuss, Jana Szolgayová, Michael Obersteiner   +3 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A real options approach to project management. [PDF]

When scheduling an uncertain project, project management may wait for additional (future) information to serve as the basis for rescheduling the project.
Boute, Robert, Demeulemeester, Erik, Herroelen, Willy   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

USING REAL OPTIONS TO EVALUATE PRODUCER INVESTMENT IN NEW GENERATION COOPERATIVES [PDF]

New Generation Cooperatives have emerged as a contemporary means for farmers to invest in further processing activities. This paper considers real options as the basis for evaluating producer investment in a start-up cooperative that involves ...
Bailey, Michael D., Sporleder, Thomas L.
core   +1 more source

A Real Options Analysis of Spacecraft Software Product Line Architectures [PDF]

, 2019
Joseph R. Laracy, Thomas J. Marlowe
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Real Options: Applications in Public Economics [PDF]

This paper illustrates the use of real options principles to value prototypical resource and industryinvestment projects. It captures important competitive/strategic dimensions in a step-by-stepanalysis of investment decisions (options) under uncertainty.
Lawrence, Craig, Thomas, Mathew
core   +1 more source